专利号:US-5693792-A 优先权日:1992-02-18 标 题 :β-lactam and cephem compounds and processes for their production 发明人:TORII SHIGERU; TANAKA HIDEO; SASAOKA MITIO; SHIROI TAKASHI; KAMEYAMA YUTAKA 权利人:OTSUKA KAGAKU KK 摘要:The object of the invention is to provide a β-lactam compound and a 2-substituted methyl-3-cephem compound, both of which are of value as intermediates for the synthesis of cephem antibiotics. n The β-lactam compound of the invention may be represented by the general formula ##STR1## wherein R 1 represents a protected amino group, for instance; R 2 represents hydrogen, for instance; R 3 represents hydrogen or a carboxy-protecting group; R 4 represents an aryl group which may be substituted; R 5 represents an alkenyl group which may be substituted, for instance. The 2-substituted methyl-3-cephem compound of the invention may be represented by the general formula ##STR2## wherein R 1 , R 2 and R 3 are as defined above; R 6 represents an aryl group which may be substituted.
专利号:WO-03061385-A1 优先权日:2002-01-17 标题:Tricyclic nucleoside library compounds, synthesis, and use as antiviral agents 发明人:AN HAOYUN; HONG ZHI; SMITH KENNETH; DING YILI; GIRARDET JEAN-LUC 权利人:RIBAPHARM INC; AN HAOYUN; HONG ZHI; SMITH KENNETH; DING YILI; GIRARDET JEAN-LUC 摘要:Tricyclic nucleoside libraries and library compounds are prepared using combinatorial chemistry and non-combinatorial chemistry methods. Contemplated library compounds are particularly useful in inhibition of viral propagation, and particularly of viral propagation of the HCV virus.
专利号:WO-2010039913-A1 优先权日:2008-10-01 标 题 :Calcilytic compounds 发明人:DEMARTINO MICHAEL P; JEONG JAE U; MARQUIS ROBERT W JR; RAMANJULU JOSHI M 权利人:GLAXOSMITHKLINE LLC; DEMARTINO MICHAEL P; JEONG JAE U; MARQUIS ROBERT W JR; RAMANJULU JOSHI M 摘要:Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.
专利号:TW-201406703-A 优先权日:2012-08-09 标 题:Synthesis method of trans-蒽二查果基诺诺
专利号:EP-0582908-B1 优先权日:1992-08-11 标 题 :2-Substituted quinolylmethoxy-phenylacetic acid- and -benzylacyl derivatives, process for their preparation and their use as inhibitors of leukotriene synthesis
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