CAS: 2832-49-7; N,N,N',N'-Tetraethylsulfamide

相似化合物

154743-05-2 1094661-86-5 33641-61-1

上下游产品

N,N-diethylsulfamoyl chloride diethylamine phenylchlorosulfate

📜二乙胺置于chlorosulfuric Acid Trifluorovinyl Ester体系中,用 乙醚 用作溶剂,化学反应生成N-三羟甲基甲基-2-氨基乙磺酸
参考文献:Fluorine-Containing-Sultones
标题:Fluorine-Containing-Sultones
摘要:
Doi:10.1007/bf00908282

专利信息

专利号:WO-2023287345-A1
优先权日:2021-07-16
标 题 :Aqueous solid phase peptide synthesis
发明人：PAWLAS JAN; LUDEMANN-HOMBOURGER OLIVIER
权利人:POLYPEPTIDE LABORATORIES HOLDING PPL AB
摘要:The present invention relates to a solid phase peptide synthesis (SPPS) where the coupling of amino acids is performed in an aqueous solution comprising at least one organic co-solvent miscible with water. The aqueous solution is capable of sufficiently solubilize the activated Fmoc-α-amine protected amino acid or activated Fmoc-α-amine protected peptide fragment, and where the resin is capable of swelling in the presence of the aqueous solution above about 4 mLg-1. The invention also encompasses a method for regeneration of spent aqueous solution from the SPPS.

专利号:WO-2024156694-A1
优先权日:2023-01-24
标 题:Method for synthesizing polypeptides
发明人：GLAFFIG MARKUS; HENNIG RABEA; HANSEN ANNA METTE; FOMSGAARD JENS; PAWLAS JAN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to a method for synthesizing a polypeptide based on solid phase peptide synthesis, the polypeptide comprising a backbone, the backbone comprising one amino acid moiety Δ selected from diamino alkanoic acids comprising from 3 up to 10 carbon atoms and one peptide side chain covalently attached to the amino acid moiety Δ, the amino acid moiety Δ being coupled to an amino acid moiety W of the backbone, the method comprising at least one reaction cycle comprising providing an amino acid building block, activating the amino acid building block in absence of a solid phase at a defined temperature and time period, and coupling the amino acid building block to the backbone.