CAS: 28047-15-6; (S)-5-Amino-5-Oxo-2-(2-Phenylacetamido)Pentanoic Acid

相似化合物

2752-35-4 163251-01-2 104771-87-1

上下游产品

CAS号56-85-9 L-谷氨酰胺 | CAS号103-80-0 苯乙酰氯 | CAS号103-82-2 苯乙酸 | CAS号6893-26-1 D-谷氨酸

D-谷氨酰胺,苯乙酰氯置于碳酸氢钠体系中,化学反应生成N-苯乙酰基-L-谷氨酰胺
参考文献:Thierfelder; Sherwin,Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie,1915,Vol. 94,P. 5
标题:Thierfelder; Sherwin,Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie,1915,Vol. 94,P. 5

专利信息

专利号:US-6372938-B1
优先权日:2001-05-21
标题:Synthesis of 4-phenylbutyric acid
发明人：BURZYNSKI STANISLAW R; MUSIAL LESZEK
权利人:BURZYNSKI STANISLAW R
摘要:A method of synthesizing compounds of Formula I:by reacting aromatic compounds with butyrolactone, followed by neutralization with base. The reaction can be conducted in the presence of a catalyst. Preferred catalysts are Lewis acids. A preferred product of Formula I is 4-phenylbutyric acid, which is obtained by the reaction of benzene with butyrolactone in the presence of aluminum chloride, followed by neutralization with base.

专利号:US-9995750-B2
优先权日:2013-12-05
标 题:Methods of detecting and measuring glutamine and analogues thereof, and methods related thereto
发明人：ACKERLEY DAVID FRANCIS; BROWN ALISTAIR SINCLAIR; ROBINS KATHERINE JANE
权利人:VICTORIA LINK LTD
摘要:Method for the detection of glutamine and its analogs are provided by the present disclosure. Also provided are methods for measuring the levels of glutamine and its analogs, including diagnostic methods. Further provided are methods that utilize glutamine analogs for the synthesis of colored pigments and other useful agents. The methods comprise the use of a nonribosomal peptide synthetase (NRPS) under conditions to produce an indigoidine or indigoidine-related pigment.

专利号:US-4016147-A
优先权日:1975-01-16
标题:Method for preparation of low-phenylalanine plastein
发明人：FUJIMAKI MASAO; ARAI SOICHI; WATANABE MICHIKO
权利人:FUJI OIL CO LTD
摘要:Method for the preparation of a low-phenylalanine plastein comprising hydrolyzing stepwise a certain albumin or globulin protein with an endopeptidase having an affinity for the aromatic acid components, and an exopeptidase, subjecting the hydrolyzate thus-obtained to gel-filtration to divide it into two fractions, one being constituted with aromatic amino acids and the other being constituted with oligopeptides almost free from the aromatic amino acids, and then subjecting the latter fraction to usual plastein synthesis. Tyrosine and/or tryptophan may be added to the substrate at the plastein synthesis in order to incorporate them into the plastein molecules. The resultant plasteins may be purified through ultra-filtration in order to remove the remaining free amino acids and low-molecular peptides.

专利号:EP-0069232-B1
优先权日:1981-07-02
标题 :Pharmaceutical composition comprising phenyl acetyl glutamine,a combination of this compound with phenylacetic acid or 3-(phenylacetylamino)piperidine-2,6-dione,a process for isolating the latter from urine and a process for the synthesis of 3-(phenylacetylamino)piperidine-2,6-dione

专利号:WO-2024102342-A1
优先权日:2022-11-10
标 题 :Combination of a glutathione synthesis inhibitor such as buthionine sulphoximine and an immune checkpoint inhibitor, preferably pembrolizumab, to treat cancer, preferably drug-resistant melanoma
发明人：SCHULTZ MICHAEL K; KAPOOR SOMYA; SPITZ DOUGLAS R
权利人:UNIV IOWA RES FOUND
摘要:The present invention relates to a process of removing free-unlabeled radionuclides from a radiopharmaceutical prior to administering the radiopharmaceutical to the patient using size-exclusion or ion-exchange mechanisms.

专利号:EP-0069232-A2
优先权日:1981-07-02
标题 :Pharmaceutical composition comprising phenyl acetyl glutamine,a combination of this compound with phenylacetic acid or 3-(phenylacetylamino)piperidine-2,6-dione,a process for isolating the latter from urine and a process for the synthesis of 3-(phenylacetylamino)piperidine-2,6-dione