CAS: 2739-98-2; Ethyl 2-Pyridylacetate

该化合物是属于酯类的有机化合物,其特征为乙酯功能组,附于一个丙烯环,特别是相对于乙酰组的2点位置.该化合物一般是无色的,可粉色黄色,具有芳香味.乙醇和乙醚等有机溶剂溶解性,但因其疏水性而在水中较易溶解.该化合物经常用于各种药品和农用化学品的合成,以及因其独特的气味而用于口味和芳香剂的应用.该化合物具有中等的挥发性,可参与各种化学反应,包括水解和转导.安全数据表明,应当谨慎处理该化合物,因为它在与皮肤或眼睛接触时可能会引起刺激.

结构式图片

相似化合物

16179-97-8 13115-43-0 103-74-2

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号5029-67-4 2-碘吡啶 | CAS号6148-64-7 丙二酸单乙酯钾盐 | CAS号5764-82-9 乙酸乙酯溴化锌 | CAS号110-86-1 吡啶 | CAS号1749-29-7 (2-Pyridylmethy... | CAS号105-58-8 碳酸二乙酯 | CAS号85274-59-5 N-phenyl-2-(pyr... | CAS号6959-47-3 2-氯甲基吡啶盐酸盐 | CAS号61890-12-8 1-phenyl-2-[2]p... | CAS号59942-87-9 吡唑并[1,5-a]吡啶-2(1H)-酮 | CAS号90-39-1 鹰爪豆碱 | CAS号267875-66-1 (2,2-difluoro-2... | CAS号267875-65-0 2,2-二氟-2-(吡啶-2-... | CAS号2739-99-3 2-(哌啶-2-基)乙酸乙酯 | CAS号15937-81-2 1,3-二(2-吡啶基)丙烷 | CAS号118667-62-2 N-B°C-2-哌啶乙酸乙酯 | CAS号13115-43-0 2-吡啶基乙酸 | CAS号64-17-5 乙醇 | CAS号103-74-2 2-吡啶乙醇

合成工艺路线路线简述

    📜吡啶置于palladium On Activated Charcoal 1,2,3,4,5,6,7,8-八硫杂环辛烷体系中,用 Various Solvent(S) 用作溶剂,化学反应生成2-吡啶乙酸乙酯
    参考文献:钛烯醇区域选择性地加成到1-酰基吡啶鎓盐中.方便合成4-(2-氧代烷基)吡啶
    标题:钛烯醇区域选择性地加成到1-酰基吡啶鎓盐中.方便合成4-(2-氧代烷基)吡啶
    摘要:烯醇钛盐加到1-苯氧羰基吡啶鎓盐的4-位上,得到1,4-二氢吡啶;随后的芳构化提供4-(2-氧代烷基)吡啶.
    Doi:10.1016/s0040-4039(01)81368-X

    海关参考信息

    专利信息


    专利号:US-8735586-B2
    优先权日:2007-06-26
    标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
    发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
    权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

    专利号:EP-2173747-B1
    优先权日:2007-06-26
    标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
    发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
    权利人:SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

    专利号:US-8926801-B2
    优先权日:2009-01-16
    标题 :Methods of electrospray chemical synthesis and device for use therein
    发明人:REHMAN ATIQ
    权利人:REHMAN ATIQ; CANAM BIORES INC
    摘要:The present invention relates to methods of production of chemical bonds and subsequent molecules by electrospray ionization and the design of an electrospray chemical synthesizer, for use in chemical synthesis and expedited organic chemical reactions.

    专利号:US-2010261909-A1
    优先权日:2007-06-26
    标题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles

    专利号:WO-2009000413-A1
    优先权日:2007-06-26
    标题:A regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles

    专利号:CA-2693142-A1
    优先权日:2007-06-26
    标题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Amit N Pandya, Et Al. Silver-Mediated Synthesis Of Indolizines Via Oxidative C-H Functionalization And 5- Endo-Dig Cyclization. Tetrahedron Lett. 2014 Dec 10;55(50):6922-6924.

    合成参考文献


    摘要:Harris, P. A., Science of Synthesis Knowledge Updates, (2021) 3, 68.
    摘要:Cheng, B.; Wang, T., Science of Synthesis Knowledge Updates, (2020) 3, 142.
    摘要:Chen, Z.-P.; Zhou, Y.-G., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 157.
    摘要:Kwiecień, H. U., Science of Synthesis: Knowledge Updates, (2024) 3, 38.
    摘要:Liao, L.; Zhang, Y.; Yu, J.-S., Science of Synthesis: Knowledge Updates, (2024) 1, 243.
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