CAS: 21609-90-5; Leptophos

结构式图片

欧盟法规

统一分类与标签压力设备指令-第1组危险流体ECHA物质ECHA物质工作场所安全标识要求C&L通报REACH预注册废弃物危险特性清单

上下游产品

CAS号1940-42-7 4-溴-2,5-二氯苯酚 | CAS号3497-00-5 苯基硫代膦酰二氯 | CAS号67-56-1 甲醇 | CAS号50654-88-1 bis(4-bromo-2,5... | CAS号6840-11-5 PHENYL-PHOSPHON...

合成工艺路线路线简述

    📜4-溴-2,5-二氯苯酚置于苄基三乙基氯化铵 Sodium Hydroxide,Potassium Carbonate体系中,用 苯 用作溶剂,化学反应 3.75H,反应生成溴苯膦
    参考文献:Purnanand; Danikhel,R. K.,Synthesis,1983,# 9,P. 731-733
    标题:Purnanand; Danikhel,R. K.,Synthesis,1983,# 9,P. 731-733

    海关参考信息

    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:WO-2021074309-A1
    优先权日:2019-10-16
    标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

    专利号:WO-2021074311-A1
    优先权日:2019-10-16
    标题:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola, Monographella nivalis, Fusarium culmorum and/or Gibberella zeae when spayed on plants) (e.g. pages 47 to 55; examples A1 and A2; compounds E.01 to E.17; table E). An exemplary compounds is e.g.: 3-(5-bromo-3,3-dimethyl-2,4-dihydro-1 H-isoquinolin-1-yl)-8-fluoro- quinoline (example A1)

    专利号:CN-113005139-B
    优先权日:2021-03-19
    标题:Application of transcription factor PsMYB1 in regulation and control of synthesis of peony petal anthocyanin

    专利号:US-7331030-B2
    优先权日:2004-12-17
    标 题 :Method to unate a design for improved synthesizable domino logic flow
    发明人:BOURGIN BERNARD
    权利人:ST MICROELECTRONICS INC
    摘要:A fully automated ASIC style domino synthesis flow is provided for mapping a digital logic design onto a domino logic library. The input to the flow is the same as for standard static synthesis environments and includes an RTL description of the design to be synthesized and a set of timing and physical constraints. The unate step includes reading the design and initializing, simplifying the logic, marking inversions, marking binate cones for duplication, identifying endpoints, performing a reverse traversal, an optional phase optimization, committing netlist changes, primary inputs processing, primary outputs processing, and a final check and save.

    专利号:WO-2021009026-A1
    优先权日:2019-07-12
    标 题 :Methyl 2-[(4-methoxyimino-tetralin-6-yl]prop-2-enoate derivatives, chromane, isochromane, 6,7,8,9-tetrahydrobenzo[7]annulene, 1h-isobenzofurane and indane analogues thereof, and similar compounds, as agrochemical fungicides
    发明人:WEISS MATTHIAS; WILLIAMS SIMON; RENDINE STEFANO; BOU HAMDAN FARHAN; HOFFMAN THOMAS; QUARANTA LAURA
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:Compounds of formula (I): (Formula (I)) Formula (I) encompasses e.g. tetraline, chromane, isochromane, 6,7,8,9-tetrahydrobenzo[7]annulene, 1H-isobenzofurane and indane derivatives. The compounds of formula (I) are useful as a pesticides, especially as fungicides. The present description discloses the synthesis and characterisation of exemplary compounds as well as biological data thereof (e.g. pages 53 to 78; examples 1 to 10; table T1; compounds 1.1 to 1.54; examples A and B). Preferred compounds are e.g.: Methyl (E)-3-methoxy-2-[(4E)-4-methoxyimino-7-methyl-tetralin-6- yl]prop-2-enoate (example 2; compound 1.6 of table T1): (Formula (A)). Methyl (E)-3-methoxy-2-[(4Z)-4-methoxyiminoisochroman-6-yl]prop-2- enoate (example 6; compound 1.39 of table T1): (Formula (B))

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Jun D, Musilova L, Pohanka M, Jung YS, Bostik P, Kuca K. Reactivation of human acetylcholinesterase and butyrylcholinesterase inhibited by leptophos-oxon with different oxime reactivators in vitro. Int J Mol Sci. 2010 Aug 3;11(8):2856-63. doi: 10.3390/ijms11082856.
    2: Yamauchi T, Konno N, Kinebuchi H. Delayed neurotoxicity resulting from administration of leptophos to the comb of domestic fowl. Tohoku J Exp Med. 1982 Oct;138(2):199-208. Japanese.

    合成参考文献


    摘要:Oyo Yakuri. Pharmacometrics., 22(373), 1981
    摘要:Journal of Agricultural and Food Chemistry., 28(594), 1980 []
    摘要:Oyo Yakuri. Pharmacometrics., 3(74), 1969
    摘要:National Technical Information Service., OTS0543229
    摘要:Fundamental and Applied Toxicology., 7(299), 1986
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知