13939-06-5 + 1780-31-0 = 2036-41-1 + 933683-35-3 反应条件:1.1 Solvents: Acetonitrile,Water; 16 H,Ph 9.5,Rt -> 45 °C1.2 Reagents: Sodium Chloride Solvents: Ethanol; Overnight,-20 °C1.3 Reagents: Cesium Hydroxide Catalysts: Palladate(1-),[2′-(Amino-Kn)[1,1′-Biphenyl]-2-Yl-Kc]Chloro[2′-(Dicyclohexylphos... Solvents: 1-Methoxy-2-Propanol,Water; 15 H,80 °C 标题:Palladium-Catalyzed Hydroxycarbonylation Of (Hetero)Aryl Halides For Dna-Encoded Chemical Library Synthesis 作者:Li,Jian-Yuan; Miklossy,Gabriella; Modukuri,Ram K.; Bohren,Kurt M.; Yu,Zhifeng; Et Al 参考文献:Bioconjugate Chemistry 日期:2019 卷标:30(8) 页码:2209-2215
5-甲基嘧啶-4-醇置于palladium-Barium Carbonate,氨,三氯氧磷体系中,化学反应生成5-甲基嘧啶 参考文献:Vanderhaeghe; Claesen,Bulletin Des Societes Chimiques Belges,1957,Vol. 66,P. 276,289 标题:Vanderhaeghe; Claesen,Bulletin Des Societes Chimiques Belges,1957,Vol. 66,P. 276,289
专利信息
专利号:US-9755163-B2 优先权日:2010-04-30 标 题:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof 发明人:LI JIAN; TURNER ERIC 权利人:ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIV; ARIZONA BOARD OF REGENTS ACTING FOR OR ON BEHALF OF ARIZONA STATE UNIV 摘要:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof.
专利号:WO-2022256490-A9 优先权日:2021-06-03 标题:Improved synthesis of phosphoramidates for the treatment of hepatitis b virus 发明人:LOCKWOOD MARK 权利人:ANTIOS THERAPEUTICS INC 摘要:The synthesis of phosphoramidate prodrugs useful in the treatment of viral infections is disclosed. Specifically, an improved synthesis of phosphoramidate nucleotides useful in the treatment of Hepatitis B virus is disclosed.
专利号:US-9126995-B2 优先权日:2011-11-08 标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound 发明人:TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU 权利人:NISSAN CHEMICAL IND LTD 摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.
专利号:US-9085538-B2 优先权日:2010-07-26 标题:Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof 发明人:CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO 权利人:CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO; LEK PHARMACEUTICALS 摘要:The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.
专利号:WO-2024137329-A1 优先权日:2022-12-20 标 题:Methods for the synthesis of complement factor d inhibitors and intermediates thereof 发明人:HASHIMOTO AKIHIRO; TIPPARAJU SURESH KUMAR 权利人:ALEXION PHARMA INC 摘要:The present disclosure provides methods for the synthesis of complement factor D inhibitors and intermediates thereof.
专利号:US-9324957-B2 优先权日:2010-04-30 标 题:Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof 发明人:LI JIAN; TUMER ERIC 权利人:LI JIAN; TUMER ERIC; UNIV ARIZONA STATE 摘要:Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof.