CAS: 14473-91-7; (E)-3-(3-Bromophenyl)Acrylic Acid

该化合物是一种有机化合物,其结构特征是其结构,其结构特征是附于其肉酸框架第三位置的溴原子,该化合物属于不饱和的碳酸类,因其芳香特性而闻名于其一个苯基组的存在;该化合物一般看起来像白色的脱白晶状固体,在水中容易溶解,但在乙醇和丙酮等有机溶剂中更容易溶解;溴基亚成分的存在能够影响其再活动,使其成为有机合成的有用中间体,特别是在各种药品和农用化学制剂的制作方面;此外,3溴辛醇酸可以进行各种化学反应,包括电子生物替代和交叉反应,这些反应在合成有机化学中是有价值的,其独特的特性和再活动使它在学术研究和工业应用中成为一种兴趣的复合物.

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合成工艺路线路线简述

    📜间溴苯胺置于盐酸体系中,化学反应生成3-溴肉桂酸
    参考文献:日本三宅岛火山岛上暖温带阔叶林的原始演替
    标题:日本三宅岛火山岛上暖温带阔叶林的原始演替
    摘要:暖温带森林的主要演替序列是从四个玄武岩火山基底(16,37 和 125 年的熔岩流,以及超过 800 年的火山喷发物)在几个海拔高度(范围从30 至 550 M)在三宅岛.物种组成的 Dca 分析表明植被是由基质年龄和海拔高度组成的.植被在各个海拔高度上依次由桤木灌木,槭树和李子林,再到栲栲林变化. 在高海拔地区,演替速度似乎更慢.在 125 年历史的熔岩流中,地上生物量分别为 20 Kg/m2 (160 M Asl) 和 12 Kg/m2 (300 M Asl),以及 54 Kg/m2 (100 M Asl) 和 16 Kg/m2 (350 M Asl) 在旧的喷射物上.然而,旧喷射物的低海拔和高海拔之间地面生物量的巨
    Doi:10.1007/bf02803192

    海关参考信息

    专利信息


    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-3975429-A
    优先权日:1973-11-05
    标题:Cyclopropanemethyl esters of cinnamic acid and derivatives thereof
    发明人:HENRICK CLIVE A; STAAL GERARDUS B
    权利人:ZOECON CORP
    摘要:Organic esters and thioesters characterized by the presence of a cyclopropane moiety, synthesis thereof, and compositions thereof for the control of mites and ticks.

    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6989384-B2
    优先权日:2000-06-14
    标题:Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
    发明人:HUA YE; LUU HIEP THE; CHAN FORA P; JOHNSON JR THEODORE O; REICH SIEGFRIED HEINZ; SKALITZKY DONALD JAMES; YANG YI; HENDRICKSON THOMAS F; CHU SHAO SONG; EASTMAN BRIAN WALTER
    权利人:AGOURON PHARMA
    摘要:Compounds of the formula: n nwhere the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Nguyen, B. N.; Hii, K. K.; Szymański, W.; Janssen, D. B., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 643.
    摘要:Zhou, Q.-Q.; Wei, Y.; Lu, L.-Q.; Xiao, W.-J., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 173.
    摘要:Ruan, Z.; Huang, Z.; Kuciński, K.; Ackermann, L., Science of Synthesis: Special Topics, (2021) 1, 231.
    摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#04755
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