CAS: 143558-00-3; Rocuronium
- 英文名称Rocuronium
- 中文名称罗库溴胺
- IUPAC名称1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium
- 其它别名r°Curonium; 1-[17β-(Acetyloxy)-3α-hydroxy-2β-morpholino-5α-androstan-16β-yl]-1-(2-propenyl)pyrrolidinium
- CAS编号143558-00-3
- MFCD编号:MFCD07364046
- 分子式:C32H53N2O4+分子量:529.79
- 产品CID: 664474
- 同类组份化合物CAS143558-00-3 (free base); 119302-91-9 (bromide)
- 产品分类原料药 → 麻醉剂 → 骨骼肌松弛药
MSDS等安全信息
- 警示词warning
- 危险描述H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
- 防范说明P264 wash thoroughly after treatmentp280 wear protective gloves / wear protective clothing / wear protective eye masks / wear protective masksp305 if in eyesp351 rinse carefully with water for a few minutesp338 remove contact lenses (if any) and easy to operate, continue rinsingp337 if eye irritation persistsp2393 get medical advice / care
- 安全声明H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
合成工艺路线路线简述
📜(5S,8R,9S,10S,13S,14S)-10,13-Dimethyltetradecahydrospiro[cyclopenta[a]Phenanthrene-17,2'-[1,3]Dioxolan]-3(2H)-One 以97的收率获得罗库溴胺
参考文献:制备表雄酮的方法
标题:制备表雄酮的方法
摘要:本发明公开了一种制备表雄酮的方法,以4-雄烯二酮(ⅰ)为原料,制备得到表雄酮,反应式如下:.本发明首次以价格低廉的4-雄烯二酮为原料,以温和的反应条件合成了表雄酮,极大地降低了生产成本,适合规模化工业生产.
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2909110000-乙醚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Guihard B, Chollet-Xémard C, Lakhnati P, Vivien B, Broche C, Savary D, Ricard-Hibon A, Marianne Dit Cassou PJ, Adnet F, Wiel E, Deutsch J, Tissier C, Loeb T, Bounes V, Rousseau E, Jabre P, Huiart L, Ferdynus C, Combes X. Effect of Rocuronium vs Succinylcholine on Endotracheal Intubation Success Rate Among Patients Undergoing Out-of-Hospital Rapid Sequence Intubation: A Randomized Clinical Trial. JAMA. 2019 Dec 17;322(23):2303-2312. doi: 10.1001/jama.2019.18254.
2: Tran DTT, Newton EK, Mount VAH, Lee JS, Mansour C, Wells GA, Perry JJ. Rocuronium vs. succinylcholine for rapid sequence intubation: a Cochrane systematic review. Anaesthesia. 2017 Jun;72(6):765-777. doi: 10.1111/anae.13903. 41(2):149-155. Chinese. doi: 10.3881/j.issn.1000-503X.11169. 71(3):397-398. doi: 10.1016/j.annemergmed.2017.04.039. Epub 2017 Jun 23. 21(17):6399. doi: 10.3390/ijms21176399.
6: Bebawy JF. Rocuronium bromide. Anesthesiology. 2011 Jun;114(6):1486. doi: 10.1097/ALN.0b013e3181fe3cea. 14(6):e01175. doi: 10.1213/XAA.0000000000001175. 42(6):203-210. doi: 10.1097/WNF.0000000000000366. 33(5):600-603. doi: 10.1007/s00540-019-02673-x. Epub 2019 Aug 21. 73(5):548-549. doi: 10.1016/j.annemergmed.2018.12.003.
📝 需求与反馈
尽可能描述清楚需求与问题信息
