CAS: 14328-62-2; (S)-Methyl 2-Amino-2-Cyclopentylacetate Hydrochloride
该化合物是化学化合物,其结构特征包括环戊烷环,乙酸基和氨基组.该化合物通常以盐盐的形式出现,表明它是基化合物的预发版,提高了其在水中的溶解度.甲基酯组的存在表明,它可以进行水解以释放相应的酸.该(S)称氨基酸的具体立体化学,这对于其生物活动和与受体的相互作用至关重要.
- 英文名称(S)-Methyl 2-Amino-2-Cyclopentylacetate Hydrochloride
- 中文名称L-环戊基甘氨酸甲酯盐酸盐
- IUPAC名称methyl (S)-2-amino-2-cyclopentylacetate hydrochloride
- 其它别名L-Cyclopentyl-Gly-Methyl Ester Hcl; L-Cyclopentylglycine Methyl Ester Hydrochloride; Methyl 2-Cyclopentyl-L-Glycinate Hcl; (S)-Amino-Cyclopentyl-Acetic Acid Methyl Ester Hydrochloride; Cyclopentaneacetic Acid, A-Amino-, Methyl Ester, Hydrochloride, (As)-; (S)-Methyl 2-Amino-2-Cyclopentylacetate; (S)-Methyl 2-Amino-2-Cyclopentylacetate Hydrochloride; -Methyl 2-Amino-2-Cyclopentylacetate Hydrochloride
- CAS编号14328-62-2
- MFCD编号:MFCD09800494
- EINECS号:108-406-0
- 分子式:C8H16ClNO2分子量:193.67
- 产品CID: 662340
- 产品分类有机原料→生命科学→氨基酸及其衍生物→甘氨酸及其衍生物
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专利信息
专利号:US-8461107-B2
优先权日:2008-04-28
标题:HCV NS3 protease inhibitors
发明人：LIVERTON NIGEL J; MCCAULEY JOHN A; BUTCHER JOHN W; GILBERT KEVIN F; MCINTYRE CHARLES J; RUDD MICHAEL T
权利人:LIVERTON NIGEL J; MCCAULEY JOHN A; BUTCHER JOHN W; GILBERT KEVIN F; MCINTYRE CHARLES J; RUDD MICHAEL T; MERCK SHARP & DOHME
摘要:The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.
专利号:US-2013178413-A1
优先权日:2010-09-21
标题 :Hcv ns3 protease inhibitors
发明人：MCCAULEY JOHN A; LIVERTON NIGEL J; RUDD MICHAEL T; GILBERT KEVIN F; FERRARA MARCO; SUMMA VINCENZO; CRESCENZI BENEDETTA
权利人:MCCAULEY JOHN A; LIVERTON NIGEL J; RUDD MICHAEL T; GILBERT KEVIN F; FERRARA MARCO; SUMMA VINCENZO; CRESCENZI BENEDETTA
摘要:The present invention relates to macrocyclic compounds of formula I that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.
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主要参考文献
[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
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