CAS: 7250-53-5; Quinoline-5-Carboxylic Acid

相似化合物

16675-62-0 22934-41-4 16178-42-0

上下游产品

5-methylquinoline meta-aminobenzoic acid glycerol potassium cyanidemethyl quinoline-5-carboxylate quinoline-5-carboxylic acid ethyl ester N-(2-Phenylethyl)-quinoline-6-carboxamide 1,2,3,4-tetrahydro-5-quinolinecarboxylic acid

专利信息

专利号:US-8188113-B2
优先权日:2006-09-14
标 题 :Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C; DECIPHERA PHARMACEUTICALS INC
摘要:The present invention relates to novel dihydropyridopyrimidinyl, dihydronaphthyridinyl, and related compounds which are kinase inhibitors and modulator useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:US-2024246060-A1
优先权日:2021-05-21
标题 :Method Of Manufacture And Scale-Up Of The Metal-Organic Framework Cu(Qc)2
发明人：ABNEY CARTER W; SEO JULIE J; KAPELEWSKI MATTHEW T; ZURLO DOMINICK A; FALKOWSKI JOSEPH M
权利人:EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY
摘要:Methods of making metal-organic frameworks in yields of at least about 50 percent by volume of metal-organic frameworks in a metal-organic framework material per liter of synthesis solution and/or about 75 molar percent of metal-organic frameworks in a metal-organic framework material are provided. Methods of making MOF Cu(Qc)2 in aqueous solutions are further provided where a solvent composition of less than about 30% volume water is combined with a buffer and a plurality of reagents to provide the synthesis solution.

专利号:US-9751874-B2
优先权日:2014-12-17
标题:Hydroxy containing FXR (NR1H4) modulating compounds
发明人：GEGE CHRISTIAN; KINZEL OLAF; KREMOSER CLAUS; SCHMITT AARON C
权利人:GILEAD SCIENCES INC
摘要:The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

专利号:US-2008045718-A1
优先权日:2006-08-14
标题 :Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives

专利号:US-5571928-A
优先权日:1994-07-26
标 题:4-amino-3-hydroxy-phthalimidine, and a process for the preparation thereof
发明人：STOLTEFUBETA JUERGEN; NEGELE MICHAEL; DUERHOLZ FRIEDRICH
权利人:BAYER AG
摘要:The present invention relates to 4-amino-3-hydroxy-phthalimidine, an important intermediate for the synthesis of 3-substituted 5-quinoline-carboxylic acid amides, and a process for the preparation thereof.

专利号:US-7985860-B2
优先权日:2006-08-14
标题:Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives
发明人：CUTARELLI TIMOTHY D; FU XIAOYONG; MCALLISTER TIMOTHY L; REEDER MICHAEL R; YIN JIANGUO; YONG KELVIN H; ZHANG SHUYI
权利人:SCHERING CORP
摘要:This application discloses a novel process to synthesize 2-(Quinolin-5yo)-4,5-Disubstituted-Azole derivatives, which may be used, for example, as PDE IV inhibitor compounds in pharmaceutical preparations.