CAS: 59227-89-3; 1-Dodecylazepan-2-One

相似化合物

19797-08-1 2556-73-2 1888-91-1

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CAS号105-60-2 己内酰胺 | CAS号143-15-7 溴代十二烷 | CAS号112-52-7 1-氯十二烷 | CAS号1634-04-4 甲基叔丁基醚 | CAS号112-53-8 月桂醇

己内酰胺置于sodium,Xylene体系中,化学反应生成 氮酮
参考文献:Synthesis Of N-Alkyldimethyl Derivatives Of ω-Amino Acids
标题:Synthesis Of N-Alkyldimethyl Derivatives Of ω-Amino Acids
摘要:
DOI:10.1021/jo50015A004

专利信息

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-6653468-B1
优先权日:2002-07-31
标 题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
权利人:ISIS PHARMACEUTICALS INC
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-2025090698-A1
优先权日:2018-11-27
标题 :Small molecule inhibitors for early diagnosis of prostate specific membrane antigen cancers and neurodegenerative diseases
发明人：CHELVAM VENKATESH; SENGUPTA SAGNIK; KRISHNAN MENA ASHA; PANDIT AMIT
权利人:INDIAN INSTITUTE OF TECH INDORE
摘要:Accordingly, embodiments herein disclose a conjugate D-E-F having binding affinity≤60 nM; wherein D comprises AAPT ligand or derivative thereof, E comprises a spacer comprising AA1, AA2, AA3 and/or AA4 and F is a chelating group. The conjugate also comprising AAPT ligand conjugated arene chelating linker for delivery of 99mTc radioisotope. Another embodiment also discloses a AAPT-PCa DOTA bioconjugate. An embodiment also discloses method of solid phase synthesis of AAPT-ligand. It also discloses a method of solid phase synthesis of AAPT-PCa DOTA bioconjugate for delivering of radioisotopes.

专利号:US-4422970-A
优先权日:1982-05-20
标题 :Method of synthesis of 1-dodecylazacycloheptan-2-one
发明人：RAJADHYAKSHA VITHAL J; PECK JAMES V; MINASKANIAN GEVORK
权利人:NELSON RES & DEV
摘要:In a method of synthesis of 1-substituted azacycloalkan-2-ones with primary alkyl halides and aralkyl halides as alkylating agents, the improvement comprising carrying out the N-alkylation in the presence of a phase transfer catalyst having the structural formula where X is suitable anion; and R1, R2, R3 and R4 are each alkyl or aralkyl groups having 1-18 carbon atoms, or R2, R3 and R4 can form a part of a heterocyclic ring, with the proviso that the combined total of carbon atoms is between 16 and 40.

专利号:WO-2008101515-A1
优先权日:2007-02-22
标 题:New synthons for the synthesis of chiral peptide nucleic acids and methods for preparing the same
发明人：BIONDI FABIO
权利人:NANODREAM S R L UNIPERSONALE; BIONDI FABIO
摘要:Novel l-acyl-3-amino-4-hydroxymethylpyiÏ„olidine derivatives useful as PNA synthons optionally having protecting groups suitable of removal under mild conditions are disclosed having the formula (E) wherein: R1 is H or R-C(=O), wherein R is straight or branched alkyl, aryl, substituted aryl including from 1 to 5 heteroatoms, a heterocyclic group including from 1 to 3 heteroatoms; R2 is H, a linker bonded to a solid support, or R6-0-C(=0), wherein R6 is an alkyl or substituted alkyl group having a tertiary carbon atom bonded to the oxygen, CHn-Arm-n wherein n is 1 or 2 and m is 2 or 3 and Ar is aryl or substituted aryl, and R3 is a nucleobase selected from thymine I, cytosine II, adenine III, guanine IV, uracil V, xanthine VI and hypoxanthine VII, a derivative of said nucleobases I-VII protected at the reactive functionalities NH2 or imidic NH, a deazacarbocyclic derivative of said nucleobases I-VII optionally protected at the reactive functionality NH2. Also disclosed are novel intermediates useful for the preparation of the aforementioned PNA synthons, as well as to methods for preparing the intermediates and the final synthons. The latter can be useful in the synthesis of peptide nucleic acids (PNAs) and other oligomers such as PNA-DNA chimeras, and may be used in automated synthesizers.

专利号:US-2024082118-A1
优先权日:2021-05-19
标 题:Topical compositions and methods of preparing the same
发明人：ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.