CAS: 5664-21-1; 2-Cyclohexylacetaldehyde

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14352-61-5 5292-21-7 4435-14-7

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CAS号4442-79-9 2-环己基乙醇 | CAS号14352-61-5 环己基乙酸甲酯 | CAS号2564-83-2 2,2,6,6-四甲基哌啶-1-氧自由基 | CAS号1193-81-3 1-环己基乙醇 | CAS号5452-75-5 环已乙酸乙酯 | CAS号98-86-2 苯乙酮 | CAS号932-89-8 2-环己基亚基乙醇 | CAS号136741-24-7 2-cyclohexyl-1,... | CAS号79-37-8 草酰氯 | CAS号65644-36-2 3-cyclohexylpro... | CAS号457-49-8 CYCLOHEXYLTRIFL... | CAS号19142-97-3 2-[(4-Cyclohexy... | CAS号5292-21-7 环己基乙酸 | CAS号82166-21-0 2-methyl cyclohexane | CAS号110-83-8 环己烯 | CAS号2109-22-0 Alpha-甲基-环己基乙醛 | CAS号67590-50-5 4-cyclohexyl-2,... | CAS号682344-42-9 3-(cyclohexylme... | CAS号3764-18-9 Hydrazinecarbox... | CAS号5136-15-2 ethyl 2,7,7-tri...

📜氯代环己烷置于水,Magnesium Oxide,三氯化铁体系中,化学反应生成 环己基乙醛
参考文献:Condensation Of Saturated Halides With Unsaturated Compounds. V. Condensation Of Cycloalkyl Halides With Ethylene And With Vinyl Halides
标题:Condensation Of Saturated Halides With Unsaturated Compounds. V. Condensation Of Cycloalkyl Halides With Ethylene And With Vinyl Halides
摘要:
DOI:10.1021/ja01170A089

专利信息

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-7276637-B2
优先权日:2002-08-02
标题:Synthesis of cyclohexanone derivatives
发明人：BRANDS KAREL MARIE JOSEPH; DAVIES ANTONY JOHN; OAKLEY PAUL JOSEPH; SCOTT JEREMY PETER; SHAW DUNCAN EDWARD; TEALL MARTIN RICHARD
权利人:MERCK & CO INC
摘要:A novel process for preparing cyclohexanone derivatives of formula (I) n nis described. The products are useful as gamma secretase inhibitors, or as intermediates in the synthesis of other gamma secretase inhibitors.

专利号:US-7423169-B2
优先权日:2001-06-11
标 题:Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
发明人：RAILLARD STEPHEN P; ZHOU CINDY X; YAO FENMEI; MANTHATI SURESH KUMAR; XIANG JIA-NING; GALLOP MARK A
权利人:XENOPORT INC
摘要:The synthesis of 1-(acyloxy)-alkyl carbamates of GABA analogs from 1-haloalkyl carbamates of GABA analogs are described. Also described are new 1-haloalkyl carbamates of GABA analogs.

专利号:US-8404088-B2
优先权日:2006-05-22
标 题:Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral bronsted acids
发明人：PORCO JR JOHN A; GERARD BAUDOUIN
权利人:PORCO JR JOHN A; GERARD BAUDOUIN; UNIV BOSTON
摘要:The present invention provides a new strategies for the synthesis of compounds of the rocaglamide family and related natural products. The synthetic approach generally involves photochemical generation of an oxidopyrylium species from a 3-hydroxychromone derivative followed by an enantioselective 1,3-dipolar cycloaddition of the oxidopyrylium species to a dipolarophile in the presence of a TADDOL derivative. This approach can be used for the formation of adducts containing an aglain core structure. Methods of the conversion of aglain core structures to aglain, rocaglamide and forbaglin ring systems are also provided. The present invention also relates to the use of rocaglamide/aglain/forbaglin derivatives for the manufacture of medicaments for use in the treatment of cancer or cancerous conditions, disorders associated with cellular hyperproliferation, or NF-κB-dependent conditions.

专利号:US-2010159540-A1
优先权日:2007-03-26
标题:Synthesis of resolvins and intermediates, compounds prepared thereby, and uses thereof
发明人：RODRIGUEZ ANA; SPUR BERND
权利人:RODRIGUEZ ANA; SPUR BERND
摘要:Methods are disclosed for the preparation of a new class of lipid mediators known as resolvins, with Resolvin D6 (4,17-dihydroxy-5E,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid) being exemplary. Also disclosed are methods for the efficient synthesis of key intermediates in the preparation of such resolvins, such as isotopically labeled ω-3 fatty acid metabolites, and derivatives and analogs thereof. The invention likewise extends to the intermediates so prepared, and to the resolvins prepared with their use.

专利号:US-9597327-B2
优先权日:2005-05-25
标 题:Synthesis of (R)-N-methylnaltrexone
发明人：DOSHAN HAROLD D; PEREZ JULIO
权利人:PROGENICS PHARM INC
摘要:This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.