CAS: 5535-52-4; P-Tolylvinylsulphone

上下游产品

2-(p-tolylsulfonyl)ethanol p-tolyl vinyl sulfide 2-chloroethyl-p-toluenesulfonate triethylamine1-[2-(toluene-4-sulfonyl)-ethyl]-piperidine 1,2-bis(p-tolylsulfonyl)ethane 3-nitro-1,5-bis-(toluene-4-sulfonyl)-pentane 3-[(4-methylbenzene)sulfonyl]propanenitrile

📜2-氯乙基对甲苯基砜置于三乙胺体系中,化学反应 24.0H,以80%的收率获得产物对甲苯基乙烯基砜
参考文献:Alonso,Diego A.; Arques,Antonio; Najera,Carmen,Anales De Quimica,1995,Vol. 91,# 5-6,P. 449-452
标题:Alonso,Diego A.; Arques,Antonio; Najera,Carmen,Anales De Quimica,1995,Vol. 91,# 5-6,P. 449-452

专利信息

专利号:WO-2007064291-A1
优先权日:2005-11-30
标 题:Method and compounds for rna synthesis
发明人：CHATTOPADHYAYA JYOTI
权利人:CHATTOPADHYAYA JYOTI
摘要:The 2-(4-tolylsulfonyl)ethoxymethyl (TEM) as a new 2'-OH protecting group is reported for the RNA synthesis on the solid support using the phosphoramidite chemistry. The usefulness of the 2'-0-TEM group is exemplified by the synthesis of 12 different oligo-RNAs of various sizes (14-38nt long). The stepwise coupling yield varied from 97 - 99 % with an optimized coupling time of 120s. Synthesis of all four pure phosphoramidite building blocks are also described. Two new reliable parameters, δc2' - δc3s and δn2' - δH3' have been suggested for the characterization of isomeric 2'-0-TEM and 3'-0-TEM as well as other isomeric mono 273 '-protected ribonucleoside derivatives. The most striking feature of this strategy is that the crude RNA prepared using our 2'-0-TEM strategy is sufficiently pure (>90 %) for molecular biology research without any additional purification step, thereby making oligo-RNAs easily available at a relatively low cost, saving both time and lab resources.

专利号:CN-105566235-A
优先权日:2016-03-03
标题:Method for step-by-step synthesis of NH-1,2,3-triazoles catalyzed by aluminum salts