CAS: 484-47-9; 2,4,5-Triphenylimidazole

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5496-32-2 1707-67-1 5496-35-5

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CAS号100-52-7 苯甲醛 | CAS号134-81-6 联苯甲酰 | CAS号119-53-9 2-羟基-2-苯基苯乙酮 | CAS号618-39-3 苯甲脒 | CAS号501-65-5 二苯乙炔 | CAS号100-47-0 苯甲腈 | CAS号573-34-2 Benzilam | CAS号631-61-8 乙酸铵 | CAS号573-33-1 2,4,5-triphenyl... | CAS号614-28-8 N-苯甲酰基-苯甲酰胺 | CAS号55-21-0 苯甲酰胺 | CAS号493-77-6 2,4,6-三苯基三嗪 | CAS号1729-09-5 4-hydroperoxy-2... | CAS号13269-91-5 1-benzyl-2,4,5-... | CAS号22397-44-0 1-methyl-2,4,5-... | CAS号55041-14-0 2-cyclohexyl-4,... | CAS号65-85-0 苯甲酸 | CAS号100-51-6 苯甲醇 | CAS号7664-41-7 氨

合成工艺路线路线简述

  • 合成目标产物 2,4,5-Triphenylimidazole 主要起始原料 Diphenylacetylene And Benzyl Alcohol
  • (文献来源)合成步骤主要原料 Diphenylacetylene 和 Benzyl Alcohol
二苯基乙酮置于ammonium Acetate,氧气体系中,用 二甲基亚砜 作为反应溶剂,化学反应 51.0H,反应生成 2,4,5-三苯基咪唑
参考文献:稳定且可重复使用的钯纳米颗粒催化合成对称和不对称 1,2-二羰基化合物
标题:稳定且可重复使用的钯纳米颗粒催化合成对称和不对称 1,2-二羰基化合物
摘要:已开发出一种使用 Dmso 作为氧化剂将 1,2-二芳基炔烃氧化为 1,2-二羰基化合物的高度稳定且可重复使用的钯纳米颗粒 (Pd-Bnp).pd-Bnp 催化体系还成功地将烯烃和脱氧安息香衍生物氧化为相应的 1,2-二羰基化合物,而无需使用任何外部添加剂.
DOI:10.1039/d2Nj05538D

海关参考信息

专利信息


专利号:US-5679773-A
优先权日:1995-01-17
标题 :Reagants and methods for immobilized polymer synthesis and display
发明人:HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:Compounds and methods for solid phase synthesis of organic molecules including peptides, oligonucleotides, benzodiazepines, beta -turn mimetics, and prostaglandins. The present invention provides new reagents in the form of linking groups and resins and substrates having attached linking groups which are useful in solid phase synthesis of high density arrays of organic molecules. The invention also provides methods which increase yields of various organic synthesis strategies.

专利号:US-2018150597-A1
优先权日:2016-11-29
标题 :Method for optimal design of polynucleotides sequences for analysis of specific events in any genetic region of interest
发明人:BERTHOUMIEUX SARA; FOURNE YANNICK; KOMATSU JUN; FER FREDERIC; BENSIMON AARON
权利人:GENOMIC VISION SA
摘要:Methods including in-silico steps for design and synthesis of Genomic Morse Code (“GMCâ€?) probes including design of combinations of polynucleotide sequences and labelling colors for analysis of large rearrangements in targeted genetic regions as well as allele characterization of complex regions and localization of events such as replication, DNA reparation or epigenetics in particular regions. Color-encoded sets of probes that produce characteristic or unique color patterns when painted on a target nucleic acid sequence. Methods for using color-encoded sets of probes.

专利号:US-2006257560-A1
优先权日:2004-12-30
标 题 :Polymer surfaces for insitu synthesis of polymer arrays
发明人:BARONE ANTHONY D; LI HANDONG; MCGALL GLENN H
权利人:AFFYMETRIX INC
摘要:In one aspect of the present invention polymers are used to create films providing three-dimensional array substrates. The films were stable and presented good hydroxyl group numbers as compared with arrays without polymer films. It is an object of the present invention that three dimensional arrays substrates provide a means to obtain higher density polymer arrays.

专利号:US-2005080260-A1
优先权日:2003-04-22
标 题 :Preparation of prodrugs for selective drug delivery
发明人:MILLS RANDELL L; WU GUO-ZHANG
摘要:Synthesis of a chemical compound having the formula A-B-C that may serve for applications such as drug delivery where A is a chemiluminescent, moiety, B is a photochromic moiety, and C is a biologically active moiety where A-B-C may serve as a prodrug. Novel synthetic methods of the present invention to form the prodrug comprised the steps of (1) forming a benzophenone, (2) forming a diaryl ethylene, (3) attaching a phthalimide moiety to at least one of the aryl groups of the ethylene to form a phthalimide-ethylene conjugate, (4) condensing two ethylene-phthalimide conjugates to form a phthalimide-pentadiene conjugate, (5) converting the phthalimide to the phthalhydrazide by reaction with hydrazine to form a carrier compound according to the present invention, and (6) reacting the carrier compound with an nucleophilic moiety of the drug to form the corresponding prodrug. Alternatively the carrier can be prepared by using the halo-substituted diaryl ethylene to make the corresponding cationic leuco dye-like compound with known methods. The cationic compound then is protected by reacting with a nucleophile and coupled with the aminophathalimide by palladium-catalyzed amination to form the protected phthalimide-pentadiene conjugate. The latter is refluxed with hydrazine to convert its phthalimide to the phthalhydrazide and acidified to give the carrier. An additional aspect of the present invention relates to the use of these compounds as antiviral agents for the treatment of viral infections such as HIV and as anticancer agents for the treatment of cancers such as bowel, lung, and breast cancer.

专利号:US-8053161-B2
优先权日:2006-09-25
标 题 :Resist composition, resin for use in the resist composition, compound for use in the synthesis of the resin, and pattern-forming method using the resist composition
发明人:WADA KENJI; SAEGUSA HIROSHI
权利人:FUJIFILM CORP
摘要:A resist composition comprises: (A) a resin capable of increasing its solubility in an alkali developer by action of an acid; (B) a compound capable of generating an acid upon irradiation with actinic ray or radiation; (C) a resin having at least one of a fluorine atom and a silicon atom; and (D) a solvent, wherein the resin (C) has a degree of molecular weight dispersion of 1.3 or less and a weight average molecular weight of 1.0×10 4 or less.

专利号:US-9709891-B2
优先权日:2005-12-09
标 题:Positive resist composition, resin used for the positive resist composition, compound used for synthesis of the resin and pattern forming method using the positive resist composition
发明人:KANDA HIROMI; KANNA SHINICHI
权利人:FUJIFILM CORP
摘要:A positive resist composition comprises: (A) a resin of which solubility in an alkali developer increases under an action of an acid; (B) a compound capable of generating an acid upon irradiation with actinic rays or radiation; (C) a resin having at least one of a fluorine atom and a silicon atom; and (D) a solvent; and a pattern forming method using the positive resist composition.
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主要参考文献


1: Honda S, Toyota T. Photo-triggered solvent-free metamorphosis of polymeric materials. Nat Commun. 2017 Sep 11;8(1):502. doi: 10.1038/s41467-017-00679-1.
2: Pavlova E, Kaloyanova S, Deligeorgiev T, Lesev N. Synthesis and physicochemical properties of novel lophine derivatives as chemiluminescent in vitro activators for detection of free radicals. Eur Biophys J. 2015 Dec;44(8):623-34. doi: 10.1007/s00249-015-1056-3. Epub 2015 Jul 30. doi: 10.1016/j.saa.2013.12.098. Epub 2014 Jan 4. doi: 10.1016/j.aca.2013.04.003. Epub 2013 Apr 10. doi: 10.1002/bio.2513. Epub 2013 Apr 30. doi: 10.1016/j.ejmech.2013.01.029. Epub 2013 Feb 4. Epub 2006 May 19. Epub 2006 Jun 6.

合成参考文献


摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#04415
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