专利号:EP-2173747-B1 优先权日:2007-06-26 标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles 发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS 权利人:SANOFI SA 摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.
专利号:CA-2693142-A1 优先权日:2007-06-26 标题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
专利号:US-4124768-A 优先权日:1975-09-24 标题:Process for preparing pure substituted 2,5-diarylamino-terephthalates and the corresponding free acids 发明人:KIRSCH ALOYS; FUCHS OTTO; SPIETSCHKA ERNST 权利人:HOECHST AG 摘要:2,5-Diarylamino terephthalates are obtained in good yields and excellent purity when the aromatic nitro compound used for oxidizing the corresponding dihydro-2,5-diarylamino terephthalate contains the aromatic radical of said diarylamino groups, i.e. when the amine formed during the oxidation is that from which said diarylamino groups device. The products yield very pure quinacridone pigments and allow the synthesis of only one isomer of substituted quinacridones.
专利号:AU-2008267443-A1 优先权日:2007-06-26 标 题 :A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
专利号:WO-2009000412-A1 优先权日:2007-06-26 标题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
专利号:JP-2010531312-A 优先权日:2007-06-26 标 题:Regioselective metal-catalyzed synthesis of fused benzimidazoles and azabenzimidazoles
参考文献:10.1023/a:1019073732760 摘要:Marziano NC, Tortato C, Ronchin L, Martini F, Bianchi C. On the acidity of liquid and solid acid catalysts. Part 2. A thermodynamic and kinetic study for acid-catalysed nitrations. Catalysis Letters. 1999 Apr;58(2-3):81–7. doi: 10.1023/a:1019073732760. 参考文献:10.1007/bf00293481 摘要:Jonquires A, Roizard D, Lochon P. Synthesis of a new styrene monomer: the 3-chloro-4-nitrostyrene. Polymer Bulletin. 1994 Sep;33(4):389–95. doi: 10.1007/bf00293481.