CAS: 3601-90-9; 1-Chloro-3,5-Di(4-Chlorbenzoyl)-2-Deoxy-D-Ribose

上下游产品

4-chloro-benzoyl chloride 1-chloro-2-deoxy-D-ribofuranose D-2-deoxyribose 1-(2'-Desoxy-3',5'-di-O-(p-chlorbenzoyl)-β-D-ribofuranosyl)-2,3-(1H,4H)-chinoxalindion 1-(2'-Desoxy-3',5'-di-O-(p-chlorbenzoyl)-α-D-ribofuranosyl)-2,3-(1H,4H)-chinoxalindion 3,5-bis-O-(p-chlorobenzoyl)-2-deoxy-D-ribofuranosyl cyanide 1-bromo-3,5-bis-O-(p-chlorobenzoyl)-2-deoxy-D-ribofuranosyl cyanide

2-Deoxy-D-Ribose置于盐酸体系中,用 吡啶,甲醇 用作溶剂,化学反应 0.75H,反应生成1-氯-3,5-二对氯苯甲酰氧基-2-脱氧-D-核糖
参考文献:Synthesis Of A Potential Antiviral Compound: 5-Bromoethynyl-2'-Deoxyuridine
标题:Synthesis Of A Potential Antiviral Compound: 5-Bromoethynyl-2'-Deoxyuridine
摘要:5-Bromoethynyluracil And Its Deoxyriboside Can Be Prepared In Good Yields Starting From Dibromovinyluracil,Which Is Accesible By Literature Methods. 5-Bromoethynyl-Deoxyuridine Is Less Effective Against Hsv-I Than E-(Bromovinyl)Deoxyuridine But,Similar To Bvdu,Seems To Exhibit A Certain Selectivity Toward Hsv-1. Molecular Calculations Prove The Spatial Similarity Of Both Compounds.
Doi:10.1016/s0040-4020(01)85560-5

专利信息

专利号:US-6716971-B1
优先权日:1998-09-08
标题:Pteridine nucleotide analogs
发明人：HAWKINS MARY E; PFLEIDERER WOLFGANG; BALIS FRANK
权利人:US HEALTH
摘要:The invention provides pteridine nucleotides of formula (I) which are highly fluorescent and which can be used in the chemical synthesis of fluorescent oligonucleotide. The invention further provides for fluorescent oligonucleotide comprising one or more pteridine nucleotides. In addition the invention provides for pteridine nucleotide triphosphates which may be used as the constituent monomers in DNA amplification procedures. The pteridine nucleotides are more stable and possess higher quantum yields than structurally similar pteridine nucleotides.

专利号:US-5612468-A
优先权日:1994-05-18
标题:Pteridine nucletide analogs as fluorescent DNA probes
发明人：HAWKINS MARY E; PFLEIDERER WOLFGANG; DAVIS MICHAEL D; BALIS FRANK
权利人:US HEALTH
摘要:The invention provides novel pteridine nucleotides which are highly fluorescent under physiological conditions and which may be used in the chemical synthesis of fluorescent oligonucleotides. The invention further provides for fluorescent oligonucleotides comprising one or more pteridine nucleotides. In addition the invention provides for pteridine nucleotide triphosphates which may be used as the constituent monomers in DNA amplification procedures.