CAS: 34696-73-6; Magnesium,1,3-Dimethylbenzene-5-Ide,Bromide

该化合物是一种在有机合成中常用的灰色试剂,用于形成碳-碳结的碳-碳联结,这种有机磁性化合物对于将3,5-二甲基苯组引入目标分子,从而能够构建复杂的芳香框架,特别宝贵;它对于碳基化合物,氧化物和卤化物等电极具有高度的回反应性,有利于在一系列反应中进行有效的调和;该试剂通常作为一种溶液在高温或二乙醚中供应,确保惰性条件下的处理稳定性和方便性;其一贯性能和选择性使得它在制药,农用化学品和材料科学方面的合成应用成为可靠的选择;在水性条件下适当储存对保持再活动至关重要.

结构式图片

欧盟法规

C&L通报

上下游产品

5-bromo-1,3-xylene magnesium 2-(3,5-dimethylbenzoyl)benzoic acid 1-(3,5-dimethylphenyl)cyclohexanol (3,5-dimethylphenyl)(phenyl)methanol 4-Hydroxy-1-methyl-4-(3.5-dimethyl-phenyl)-cyclohexan

合成工艺路线路线简述

    📜3,5-二甲基溴苯 反应生成3,5-二甲基苯基溴化镁
    参考文献:Carr,Albert A.;Wiech,Norbert L.
    标题:Carr,Albert A.;Wiech,Norbert L.

    海关参考信息

    专利信息


    专利号:US-8487108-B2
    优先权日:2005-11-14
    标题 :Piperidinyl carbamate intermediates for the synthesis of aspartic protease inhibitors
    发明人:BALDWIN JOHN J; CLAREMON DAVID A; TICE COLIN; CACATIAN SALVACION; DILLARD LAWRENCE W; ISHCHENKO ALEXEY V; YUAN JING; XU ZHENRONG; MCGEEHAN GERARD; SIMPSON ROBERT D; SINGH SURESH B; ZHAO WEI; FLAHERTY PATRICK T
    权利人:BALDWIN JOHN J; CLAREMON DAVID A; TICE COLIN; CACATIAN SALVACION; DILLARD LAWRENCE W; ISHCHENKO ALEXEY V; YUAN JING; XU ZHENRONG; MCGEEHAN GERARD; SIMPSON ROBERT D; SINGH SURESH B; ZHAO WEI; FLAHERTY PATRICK T; VITAE PHARMACEUTICALS INC
    摘要:The present invention is directed to aspartic protease inhibitors. Certain aspartic protease inhibitors of the invention can be represented by the following structural formula or a pharmaceutically acceptable salt thereof. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.

    专利号:US-4804679-A
    优先权日:1984-07-24
    标 题:Erythro-(E)-7-(3'-C1-3alkyl-1'-(3',5'-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
    发明人:ANDERSON PAUL L
    权利人:SANDOZ PHARMACEUTICALS CORP
    摘要:Compounds of the formula wherein R1 is C1-3alkyl, and Z is wherein R7 is hydrogen, R8 or M, wherein R8 is a physiologically acceptable and hydrolyzable ester group, and M is a pharmaceutically acceptable cation, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

    专利号:CN-115028641-A
    优先权日:2022-07-19
    标题:A method for cobalt-catalyzed synthesis of 5,8-difunctional substituted imidazo[1,2-a]pyrazine compounds

    专利号:US-5753675-A
    优先权日:1989-03-03
    标 题:Quinoline analogs of mevalonolactone and derivatives thereof
    发明人:WATTANASIN SOMPONG
    权利人:NOVARTIS PHARMACEUTICALS CORP
    摘要:Quinoline analogs of mevalonolactone of the following formula are useful as anti-cholesterol synthesis agents: where the substituents are as defined in the specification.

    专利号:US-4686237-A
    优先权日:1984-07-24
    标题 :Erythro-(E)-7-[3'-C1-3 alkyl-1'-(3',5'-dimethylphenyl)naphth-2'-yl]-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
    发明人:ANDERSON PAUL L
    权利人:SANDOZ PHARMACEUTICALS CORP
    摘要:Compounds of the formula wherein R1 is C1-3alkyl, and Z is wherein R7 is hydrogen, R8 or M, wherein R8 is a physiologically acceptable and hydrolyzable ester group, and M is a pharmaceutically acceptable cation, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

    专利号:US-11542346-B2
    优先权日:2018-03-19
    标 题 :Catalysts for olefin polymerization
    发明人:IZMER VYATCHESLAV V; KONONOVICH DMITRY S; VOSKOBOYNIKOV ALEXANDER Z; VIRKKUNEN VILLE; RESCONI LUIGI MARIA CRISTOFORO
    权利人:BOREALIS AG
    摘要:New bisindenyl ligand complexes and catalysts comprising those complexes. The invention is directed to improving the manufacturing of specific C1-symmetric bisindenyl complexes by modifying one of the indenyl ligands in order to improve the selectivity of the complex synthesis towards the desired anti-isomer, increase the yield and simplify the purification of the complex. The invention also relates to the use of the new bisindenyl metallocene catalysts for the production of polypropylene homopolymers or propylene copolymers.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Lu, J.-M.; Shao, L.-X., Science of Synthesis Knowledge Updates, (2020) 3, 362.
    摘要:Pilgrim, B. S.; Tucker, M. J., Science of Synthesis Knowledge Updates, (2019) 1, 293.
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