专利号:US-2024043406-A1 优先权日:2020-12-18 标题 :Method for sequential one-pot synthesis of tkx-50 发明人:DELAGE ARTHUR; ECK GENEVIÈVE; ALAIME THIBAUD; LACEMON FRÉDÉRICK; KLAPOTKE THOMAS; STIERSTORFER JORG; BOLTER MARC 权利人:EURENCO FRANCE 摘要:The present invention relates to a sequential one-pot synthesis of TKX-50, suitable for larger-scale production, during which an acetyl halide is used during the cyclization of diazidoglyoxime so as to obtain 1,1′-diacetyl-5,5′-bistetrazole, which is then hydrolyzed to 5,5′-bistetrazole-1,1′-diolate, to which compound a hydroxylammonium salt is subsequently added.
专利号:EP-4263527-A1 优先权日:2020-12-18 标题 :Method for sequential one-pot synthesis of tkx-50
专利号:WO-2022129724-A1 优先权日:2020-12-18 标 题:Method for sequential one-pot synthesis of tkx-50
专利号:FR-3118034-A1 优先权日:2020-12-18 标题 :Process for the sequential one-pot ('one-pot') synthesis of TKX-50
参考标题:Solid-Phase Versus Solution Synthesis Of Asymmetrically Disubstituted Furazano[3,4-B]Pyrazines 作者:E. Fernández,S. Garcı́a-Ochoa,S. Huss,A. Mallo,J.M. Bueno,F. Micheli,A. Paio,E. Piga,P. Zarantonello |发布日期:2002.7 摘要:Herein We Describe A Straightforward Solid-Phase Synthesis Directed Towards The Preparation Of Families Of Asymmetrically Disubstituted Furazano[3,4-B]Pyrazines By Stepwise Displacement Of The Two Chlorine Atoms In 5,6-Dichlorofurazano[3,4-B]Pyrazine By Nucleophiles. This Synthesis Has Avoided Selectivity Problems Found In Solution Chemistry.
合成参考文献
摘要:H. E. Ungnade, L. W. Kissinger, A. Narath and D. C. Barham, J. Org. Chem. 28, 134 (1963). 摘要:P. E. Wenger, O. Monnier and I. Kapetanidis, Helv. Chim. Acta 40, 1456 (1957).