专利号:US-6872716-B2 优先权日:2000-09-11 标题:Antipsychotic sulfonamide-heterocycles, and methods of use thereof 发明人:WU XINHE; AQUILA BRIAN M; SHAO LIMING; RADEKE HEIKE; CUNY GREGORY D; HAUSKE JAMES R; XIE ROGER L 权利人:SEPRACOR INC 摘要:One aspect of the present invention relates to heterocyclic compounds comprising a sulfonamide moiety. A second aspect of the present invention relates to the use of the heterocyclic compounds comprising a sulfonamide moiety to treat diseases, afflictions or maladies caused at least in part by abnormal activity of one or more GPCRs or ligand-gated ion channels. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the heterocyclic compounds comprising a sulfonamide moiety, and the screening of those libraries for biological activity, e.g., in animal models of psychosis.
专利号:US-4681894-A 优先权日:1986-09-26 标题:Hydroxamic acids and esters 发明人:MURRAY WILLIAM V; WACHTER MICHAEL P 权利人:ORTHO PHARMA CORP 摘要:The synthesis of amido substituted naphthalenes and their intermediates is described. The intermediates and amido substituted naphthalenes are useful as anti-inflammatory agents.
专利号:US-4814487-A 优先权日:1986-09-26 标 题:Amido substituted naphthalenes and intermediates thereof 发明人:MURRAY WILLIAM V; WACHTER MICHAEL P 权利人:ORTHO PHARMA CORP 摘要:The synthesis of amido substituted naphthalenes and their intermediates is described. The intermediates and amido substituted naphthalenes are useful as anti-inflammatory agents.
专利号:CN-115385765-A 优先权日:2022-01-05 标 题:Synthesis method of alkyl aryl ketone
专利号:CN-115385765-B 优先权日:2022-01-05 标题:A kind of synthesis method of alkyl aryl ketone
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