CAS: 10167-23-4; (2-Nitrobenzoyl)Glycine

该化合物是一种有机化合物,其特点是以2-硝基苯甲酰基组进行改造的甘蓝混合物,其结构特征包括一个氨基氨基酸组,一个碳本体酸组和一个硝基替代芳香环.硝基甲基苯基甲酸组的存在通常具有独特的电子特性,影响该化合物在包括药物和生物化学在内的各个领域的回动和潜在应用.甘基辛本身是最简单的氨基甲硫,其衍生物往往展示出有趣的生物活动.引入2硝基乙酰基苯乙烯组可以提高该化合物的溶性性和稳定性,使之适合用于合成,并成为生产更复杂的分子的潜在中间体.此外,该化合物还可能表现出与生物目标的具体互动,可以用于治疗目的.总体而言,甘基尼,N-(2-硝基本酰基)是化学研究与开发的宝贵化合物.

结构式图片

相似化合物

256657-23-5 526-21-6 5177-51-5

物理性质

MSDS等安全信息

欧盟法规

C&L通报

上下游产品

CAS号56-40-6 甘氨酸 | CAS号610-14-0 2-硝基苯甲酰氯 | CAS号5177-49-1 ETHYL 2-(2-NITR... | CAS号552-16-9 2-硝基苯甲酸 | CAS号623-33-6 甘氨酸乙酯盐酸盐 | CAS号5118-94-5 苯并-1,4-二氮杂卓-2,5-二酮 | CAS号526-21-6 N-(2-氨基苯甲酰基)甘氨酸

合成工艺路线路线简述

    📜Ethyl 2-(2-Nitrobenzamido)Acetate置于水,Sodium Hydroxide体系中,用 2-甲基四氢呋喃 用作溶剂,化学反应 1.0H,反应生成N-(2-硝基苯甲酰基) 甘氨酸
    参考文献:Substituents Effect On The Erlenmeyer−plöchl Reaction: Understanding An Observed Process Reaction Time
    标题:Substituents Effect On The Erlenmeyer−plöchl Reaction: Understanding An Observed Process Reaction Time
    摘要:A Systematic Study On Hippuric Acid Substituents Was Performed In Order To Better Understand The Influence Of Stereoelectronic Factors On The Erlenmeyer Reaction Rate. In Addition,Two Reaction Systems Were Evaluated: Hunig'S Base Solvent Free Conditions And Catalytic Sodium Acetate In 2-Methyl-Thf. The Effect On Reaction Rate Of Electron Withdrawing And Electron Donating Groups Are Reported. Specifically,The Study Led To The Conclusion That Stereoelectronic Factors Have Significant Influence In One Of Our Key Erlenmeyer Reaction By Affecting Its Reaction Rate.
    Doi:10.1021/op100032S

    海关参考信息

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:O-Nitrobenzoyl Group As A New Amino Protecting Group For Peptide Synthesis And The Synthesis Of Some Anthranilyl Peptides
    作者:A.K. Koul,J.M. Bachhawat,B. Prashad,N.S. Ramegowda,A.K. Mathur,N.K. Mathur |发布日期:1973.1
    摘要:And The Resulting Product On Hydrogenation Gives Peptides, Containing The Anthranilyl Group As -Nh2 End Group. N (Anthranilyl)Amino Acids Or Peptides Can Also Be Obtained By Reaction Of Isatoic Anhydride On Amino Acids Or Peptides. The Anthranilyl End Group Is Easily Cleaved By Metal (Cu+2) Catalysed Hydrolysis To Give α-Amino Acid Peptides And The Insoluble Copper(II) Anthranilate.

    合成参考文献


    参考文献:10.1007/bf03189474
    摘要:Tuong A, Bouyssou A, Paret J, Cuong TG. Metabolism of triclopidine in rats: Identification and quantitative determination of some its metabolites in plasma, urine and bile. European Journal of Drug Metabolism and Pharmacokinetics. 1981 Apr;6(2):91–8. doi: 10.1007/bf03189474.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知