CAS: 46392-44-3; Ethyl-Dicyclohexyl-Phosphin

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ethylmagnesium bromide chlorodicyclohexylphosphaneAethyl-dicyclohexyl-phosphinoxyd Methyl-ethyl-dicyclohexyl-phosphonium

合成工艺路线路线简述

    📜二环己基氯化膦,Alkaline Earth Salt Of/the/ Methylsulfuric Acid 以 乙醚 作为反应溶剂,化学反应生成 二环己基(乙基)膦
    参考文献:Payne,Nicholas C.; Stephan,Douglas W.,Canadian Journal Of Chemistry,1980,Vol. 58,# 1,P. 15-21
    标题:Payne,Nicholas C.; Stephan,Douglas W.,Canadian Journal Of Chemistry,1980,Vol. 58,# 1,P. 15-21

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    专利信息


    专利号:US-8188282-B2
    优先权日:2006-07-15
    标 题:Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles
    发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; HALLAND NIS; RKYEK OMAR; URMANN MATTHIAS
    权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; HALLAND NIS; RKYEK OMAR; URMANN MATTHIAS; SANOFI AVENTIS
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct palladium catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides useful for the production of pharmaceuticals, diagnostic agents, liquid crystals, polymers, herbicides, fungicidals, nematicidals, parasiticides, insecticides, acaricides and arthropodicides.

    专利号:US-2025002518-A1
    优先权日:2023-06-16
    标 题 :Synthesis of heteroarynes and use thereof
    发明人:MATTMILLER ROBERTS COURTNEY COLLEEN; HUMKE JENNA NICOLE; QUINLIVAN ANSEL ANNABEL; BELLI ROMAN GIANCARLO; KARGBO SALLU SO; PLASEK ERIN ELIZABETH
    权利人:UNIV MINNESOTA
    摘要:Disclosed herein are heterocyclic arynes and methods for preparing the same. Heteroarynes such as 5-membered O- or N-heterocyclic arynes have been considered inaccessible due to ring strain associated with the triple bond. The methods described herein demonstrate that these arynes can be successfully prepared through the utility of pi-backbonding from a transition metal. Synthetic utility of this method has been demonstrated by the facile synthesis and functionalization of heterocycles using these heteroaryne building blocks.

    专利号:US-10457640-B2
    优先权日:2016-10-19
    标 题:Synthesis of inhibitors of EZH2
    发明人:VASWANI RISHI G; HEWITT MICHAEL CHARLES
    权利人:CONSTELLATION PHARMACEUTICALS INC
    摘要:Provided herein are synthetic methods for the preparation of EZH2 inhibitors.

    专利号:US-8487109-B2
    优先权日:2007-07-03
    标题:Process for the palladium-catalyzed coupling of terminal alkynes with aryl tosylates
    发明人:RKYEK OMAR; NAZARE MARC; LINDENSCHMIDT ANDREAS; URMANN MATTHIAS; HALLAND NIS; ALONSO JORGE
    权利人:RKYEK OMAR; NAZARE MARC; LINDENSCHMIDT ANDREAS; URMANN MATTHIAS; HALLAND NIS; ALONSO JORGE; SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), n nwherein R1; R2; R3; R4; R5; J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process for aryl tosylates with terminal alkynes to a wide variety of substituted, multifunctional aryl-1-alkynes of the formula I.

    专利号:US-8420812-B2
    优先权日:2007-07-03
    标题:Process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonates
    发明人:RKYEK OMAR; NAZARE MARC; LINDENSCHMIDT ANDREAS; ALONSO JORGE; URMANN MATTHIAS; HALLAND NIS
    权利人:RKYEK OMAR; NAZARE MARC; LINDENSCHMIDT ANDREAS; ALONSO JORGE; URMANN MATTHIAS; HALLAND NIS; SANOFI SA
    摘要:A process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonates n The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), n nwherein D, J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process of heteroaryl tosylates with terminal alkynes to a wide variety of substituted, multifunctional heteroaryl-1-alkynes of the formula I.

    专利号:US-3843719-A
    优先权日:1969-05-14
    标 题 :Synthesis of esters
    发明人:BRADY D
    权利人:PHILLIPS PETROLEUM CO
    摘要:Preparation of esters of carboxylic acids in improved yields in shorter reaction times by use as catalysts organic compounds and complexes of certain Group VA and VIA elements. The method optionally uses a soluble iodide for further increase in yield.

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    合成参考文献


    参考文献:10.1007/978-1-4899-6848-7_19
    摘要:MacIntyre JE. Fe Iron. 1996. In: Dictionary of Organometallic Compounds.
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