CAS: 15299-99-7; Napropamide

该化合物是一种选择性除草剂,主要用于控制各种作物中每年的草和某些大叶杂草,属于乙酰胺除草剂类别和功能,抑制目标植物细胞分裂,有效防止其生长;在化学上,氨丙胺的特点是水溶性相对较低,有助于其在土壤中的持久性和作为发芽前除草剂的功效;通常在除草种子发芽前对土壤施用,形成阻隔新出现杂草生长的障碍;氨丙胺具有中度毒性特征,在使用标签指示时一般认为其环境影响是可以控制的;使用者必须遵守安全准则和条例,以尽量减少对非目标生物和环境的潜在风险;

结构式图片

欧盟法规

ECHA物质欧盟农药活性物质ECHA物质C&L通报REACH预注册

上下游产品

α-naphthol diethylamine (R,S)-2-chloropropionic acid(R)-napropamide (S)-napropamide

合成工艺路线路线简述

    📜萘酚置于吡啶,四溴化碳,Potassium Carbonate,Sodium Hydroxide体系中,用 四氢呋喃,水,丙酮,乙腈 用作溶剂,化学反应 30.0H,反应生成敌草胺
    参考文献:通过吡啶-Cbr4 的新型羧酸光活化模式直接形成酰胺键的高效光介导方案
    标题:通过吡啶-Cbr4 的新型羧酸光活化模式直接形成酰胺键的高效光介导方案
    摘要:提出了利用吡啶-Cbr 4的新型光活化模式,由羧酸和胺或氨基酸uva光介导合成酰胺.Di-Hrms 的机理研究为各种中间体的形成提供了实验证据.展示了在工业上有趣的或生物活性化合物的合成中的应用.
    Doi:10.1002/chem.202300556

    海关参考信息

    专利信息


    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

    专利号:ES-2717283-T3
    优先权日:2012-07-24
    标 题:Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and herbicides inhibitors of VLCFA synthesis and synthesis of fatty acids / lipids

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Qi Y, Liu D, Zhao W, Liu C, Zhou Z, Wang P. Enantioselective phytotoxicity and bioacitivity of the enantiomers of the herbicide napropamide. Pestic Biochem Physiol. 2015 Nov;125:38-44. doi: 10.1016/j.pestbp.2015.06.004. Epub 2015 Jun 13. Review. doi: 10.1002/chir.22277. Epub 2014 Jan 17. doi: 10.1107/S1600536813017947. eCollection 2013.
    4: Sadegh-Zadeh F, Wahid SA, Seh-Bardan BJ, Othman R, Omar D. Fate of napropamide herbicide in selected Malaysian soils. J Environ Sci Health B. 2012;47(2):144-51. doi: 10.1080/03601234.2012.624481. doi: 10.1016/j.jhazmat.2011.02.086. Epub 2011 Mar 6. doi: 10.13287/j.1001-9332.201610.017. Chinese. doi: 10.1021/jf9027766. doi: 10.1007/s00244-009-9426-4. Epub 2009 Dec 5. doi: 10.1016/j.chroma.2016.10.029. Epub 2016 Oct 13. doi: 10.1039/b713369c. Epub 2007 Oct 31. Chinese. Epub 2007 Oct 9. doi: 10.1016/j.talanta.2011.03.067. Epub 2011 Apr 5. Chinese.

    合成参考文献


    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2014) 4, 182.
    摘要:Pesticide & Toxic Chemical News., 8(22), 1980
    摘要:Lide, D.R. (ed.). CRC Handbook of Chemistry and Physics. 79th ed. Boca Raton, FL: CRC Press Inc., 1998-1999., p. 3-222
    摘要:USEPA/Office of Water; Federal-State Toxicology and Risk Analysis Committee (FSTRAC). Summary of State and Federal Drinking Water Standards and Guidelines (11/93) To Present
    摘要:USEPA/OPP; Status of Pesticides in Registration, Reregistration and Special Review p.193 (Spring, 1998) EPA 738-R-98-002
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知