CAS: 13832-70-7; Stearyl Glycyrrhetinate

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CAS号112-92-5 硬脂醇 | CAS号471-53-4 甘草次酸; beta-甘草亭酸 | CAS号135459-36-8 30-stearyl glyc...

30-Stearyl Glycyrrhizin置于硫酸体系中,化学反应生成硬脂醇甘草亭酸酯
参考文献:Synthetic Studies On The Relationship Between Anti-Hiv Activities And Micelle Forming Abilities Of Various Alkylated Glycyrrhetinate Diglycoside Sodium Sulfates And Related Compounds
标题:Synthetic Studies On The Relationship Between Anti-Hiv Activities And Micelle Forming Abilities Of Various Alkylated Glycyrrhetinate Diglycoside Sodium Sulfates And Related Compounds
摘要:Sodium Sulfates 11-14,29-32,35 And 37 Of Various Alkyl Glycyrrhizin And Related Compounds Were Synthesized. In Vitro Anti-Hiv Activities Of The Sulfates Were Compared To The Activities Of Glycyrrhizin 1 In The Inhibition Of Replications Of Htlv-Iii And Gun-4. The Activities Of The Sulfates Were Increased 11.1,15.2,9.1 And 5.0 Times For 11-14,100.0,125.5,83.3 And 11.6 Times For 29-32,And 11.6 And 50.0 Times For 35 And 37. From The Relationship Between Cmc Values And Anti-Hiv Activities Of The Sulfates,It Appeared That The Sulfates Exhibiting More Potent Antiviral Activities Had Higher Micelle Forming Abilities. Sodium Sulfates Having A Triterpenoid Or Steroid Ring In The Molecule Showed More Potent Activities Than Those Of Thioglycosides Which Had No Such Ring. From The Investigation Of Syncytium Formation,We Suggest That The Active Sulfates Inhibited Hiv-1 Infection Early In The Replication Cycle Of The Virus.
Doi:10.1016/0223-5234(96)89163-X

专利信息

专利号:WO-2005079742-A1
优先权日:2004-02-19
标 题:Cosmetic and/or dermatological agent for increasing the endogenous lipid content of the skin
发明人：VEEGER MARCEL; KLOTZ ANDREAS; ZUR MUEHLEN ANNETTE; THOERNER BRIGITTE
权利人:STOCKHAUSEN CHEM FAB GMBH; VEEGER MARCEL; KLOTZ ANDREAS; ZUR MUEHLEN ANNETTE; THOERNER BRIGITTE
摘要:The invention relates to the use of at least one active ingredient that is selected from the water-soluble groups: (a) allantoin; (b) salts and/or esters of gluconic acid and/or aspartic acid; (c) precursors of creatine, creatine and creatinine and their derivatives; (d) glycyrrhetinic acid or the salts and/or esters thereof; (e) D-panthenol and/or at least one active ingredient that is selected from the oil-soluble groups: (f) vitamin E acetate; (g) cholesterol; (h) derivatives of glycyrrhetinic acid, in so far as they are soluble in the oils and fats that are conventionally used in the cosmetic industry; (i) vegetable oils and fats; (j) non-saponifiable fractions of vegetable fats. Said active ingredients are used alone or in combination with one or more active ingredients from the groups (a) to (j) to produce a cosmetic and/or dermatological agent for stimulating the endogenous synthesis of barrier substances, in particular for increasing the endogenous lipid content of the skin.

专利号:US-7087743-B2
优先权日:2000-02-11
标 题 :Oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents
发明人：KURFURST ROBIN; JOLY REGINE
权利人:LVMH RECH
摘要:The present invention relates to novel oligonucleotide sequences and also to derivatives thereof. n These novel oligonucleotide sequences are capable of hybridizing specifically with the gene or with a product of the gene encoding tyrosinase, or with the gene or a product of the gene encoding tyrosinase-related-protein 1 (TRP-1). n The present invention also relates to the use of these novel oligonucleotide sequences as a depigmenting or bleaching agent in a cosmetic composition or in a dermatological composition.

专利号:WO-2006097348-A1
优先权日:2005-03-15
标 题:Use of agents such as nonpolymeric nitric oxide donors for making the lips full again and/or colouring the lips
发明人：CALS-GRIERSON MARIE-MADELEINE
权利人:OREAL; CALS-GRIERSON MARIE-MADELEINE
摘要:The invention relates in particular to the cosmetic use (i) of at least one agent for promoting the production of NO in and/or on the lips, chosen from nitric oxide NO donors or precursors; nonpolymeric NO releasers; and NO synthase synthesis and/or activity stimulators; or (ii) of other agents for promoting microcirculation in the skin, chosen from potassium channel openers; calcium channel blockers; phosphodiesterase inhibitors; flavonoids; vasodilator peptides that are not NO donors; temperature modulators; agents for promoting the stimulation and/or maintenance of angiogenesis; agents for promoting the stimulation of endothelial cell proliferation; agents for promoting endothelial cell migration; and mixtures thereof, in a makeup and/or care composition for the lips, as an agent for naturally making the lips full again and/or naturally coloring the lips. It also relates to specific care and/or makeup compositions for the lips containing said agent, and also to a cosmetic process aimed at making the lips naturally full and/or colored, using said compositions .

专利号:CN-101067135-A
优先权日:2000-02-11
标题 :Novel oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents

专利号:JP-2008043334-A
优先权日:2000-02-11
标 题:New oligonucleotide and use of oligonucleotide modulating expression of enzyme involved in synthesis of melanic pigment, as decolorant

专利号:EP-1255827-B1
优先权日:2000-02-11
标 题 :Oligonucleotides and their use for modulating the expression of tyrosinase involved in the synthesis of melanic pigments