CAS: 1127-76-0; 1-Ethylnaphthalene

相似化合物

939-27-5 2765-18-6 6158-45-8

上下游产品

1'-naphthacetophenone ethyl bromide 1-Bromonaphthalene 1-vinylnaphthalene 1-vinylnaphthalene 4-ethyl-1-naphthalenecarboxylic acid 2-ethylnaphthalene 5-ethyltetralin

📜1-萘甲醇置于1,8-二氮杂双环[5.4.0]十一碳-7-烯体系中,用 正己烷,二氯甲烷 用作溶剂,化学反应 4.0H,反应生成1-乙基萘
参考文献:三甲基铝置换三氯乙酰亚胺酯合成1,1'-二芳基乙烷及相关体系
标题:三甲基铝置换三氯乙酰亚胺酯合成1,1'-二芳基乙烷及相关体系
摘要:在路易斯酸促进的条件下,三氯乙酰亚胺酸苄酯很容易被三甲基铝取代,以提供相应的甲基取代产物.该方法是获取 1,1'-二芳基乙烷和相关系统的便捷方法,这些系统在药物化学中发挥着重要作用,许多系统的生物活性归功于此功能.大多数苄基底物都会发生位移,但缺电子系统除外.对映体纯亚氨酸酯的使用显示出显着的外消旋作用,表明形成了阳离子中间体.
Doi:10.1021/acs.Joc.8B00027

专利信息

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-7423169-B2
优先权日:2001-06-11
标 题:Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
发明人：RAILLARD STEPHEN P; ZHOU CINDY X; YAO FENMEI; MANTHATI SURESH KUMAR; XIANG JIA-NING; GALLOP MARK A
权利人:XENOPORT INC
摘要:The synthesis of 1-(acyloxy)-alkyl carbamates of GABA analogs from 1-haloalkyl carbamates of GABA analogs are described. Also described are new 1-haloalkyl carbamates of GABA analogs.

专利号:US-8101804-B2
优先权日:2006-07-28
标 题 :Process for the synthesis of (E)-stilbene derivatives which makes it possible to obtain resveratrol and piceatannol
发明人：SCHOUTEETEN ALAIN; JUS SEBASTIEN; VALLEJOS JEAN-CLAUDE
权利人:SCHOUTEETEN ALAIN; JUS SEBASTIEN; VALLEJOS JEAN-CLAUDE; CLARIANT SPECIALTY FINE CHEM F
摘要:A subject-matter of the present invention is a novel process for the synthesis of (E)-stilbene derivatives targeted at obtaining in particular resveratrol and piceatannol.

专利号:US-7632975-B2
优先权日:2004-12-22
标 题:Process for the synthesis of arylfluorenes and analogs thereof
发明人：HEIDENHAIN SOPHIE
权利人:CDT OXFORD LTD
摘要:A process is provided for the synthesis of a compound of formula (I): n nwherein:n M=0 or 1; N and p are 0 or 1 to 4; X is a single bond, O, S or NH; And R 1 -R 4 are as defined in claim 1.

专利号:US-9676726-B2
优先权日:2013-12-23
标题:Process for the regioselective synthesis of pyrazoles
发明人：MEAZZA GIOVANNI; SILLANI LAURA; MEREGHETTI PIERANGELO; FORGIA DANIELE
权利人:ISAGRO SPA
摘要:A process is described for the synthesis of pyrazoles having general formula (I) n nwhich comprises the steps of mixing a compound having general formula (II)n n nand a 1,2-disubstituted hydrazine having general formula (III)n n nto form a reaction intermediate having general formula (IV)n n nand the reaction mixture obtained in step i), in an acid environment, cyclizes to form a pyrazole having general formula (I), according to reaction scheme 1

专利号:US-8399714-B2
优先权日:2007-10-03
标题 :Process for the synthesis of polyhydroxystilbene compounds
发明人：VALLEJOS JEAN-CLAUDE; SCHOUTEETEN ALAIN; WILHELM DIDIER
权利人:VALLEJOS JEAN-CLAUDE; SCHOUTEETEN ALAIN; WILHELM DIDIER; CLARIANT SPECIALITY FINE CHEMICALS FRANCE
摘要:The invention relates to a process for the synthesis of stilbene derivatives of formula (I)-(E) or (I)-(Z) n nin which R represents hydrogen or an OH group,n nby deprotection in the presence of an aluminum halide and of a tertiary amine of a compound of formula (II)-(E) or (II)-(Z)n n nin which A represents hydrogen or an OR′ 1 group, and R 1 , R 2 , R 3 and R′ 1 independently represent an alkyl or aralkyl group.