CAS: 107316-88-1; (2R,4As,6As,12Br,14As,14Br)-9-Formyl-10,11-Dihydroxy-2,4A,6A,12B,14A-Pentamethyl-8-Oxo-1,2,3,4,4A,5,6,6A,8,12B,13,14,14A,14B-Tetradecahydropicene-2-Carboxylic Acid
该化合物是一种化学化合物,属于类固醇,是类固醇,是类固醇,其特点是复杂的多环结构,包括典型的类固醇化合物的多发引信环,该物质主要来自天然来源,通常与植物材料分离,以其潜在的生物活动,包括抗炎和抗氧化特性而闻名.二甲基隔热物质也可能对脂类新陈代谢产生影响,并研究其潜在的治疗用途.其溶解性特征通常表明,它比水中的有机溶剂更具溶性,而水是许多酯类的常见现象.该化合物的稳定性和再活动性可能受其功能组的影响,其结构中存在双重结合.与许多酯类一样,它可以在细胞过程和膜动态中发挥作用,因此对药理学和生物化学研究都感兴趣.
- 英文名称(2R,4As,6As,12Br,14As,14Br)-9-Formyl-10,11-Dihydroxy-2,4A,6A,12B,14A-Pentamethyl-8-Oxo-1,2,3,4,4A,5,6,6A,8,12B,13,14,14A,14B-Tetradecahydropicene-2-Carboxylic Acid
- 中文名称去甲泽拉木醇
- IUPAC名称(2R,4aS,6aS,12bR,14aS,14bR)-9-formyl-10,11-dihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid
- 其它别名demethylzeylasteral; (9beta,13alpha,14beta,20alpha)-2,3-Dihydroxy-9,13-dimethyl-6,23-dioxo-24,25,26-trinoroleana-1,3,5(10),7-tetraen-29-oic acid
- CAS编号107316-88-1
- MFCD编号:MFCD16660658
- 分子式:C29H36O6分子量:480.6
- 产品CID: 111790
- 产品分类生物化工 → 提取物
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2905141000-异丁醇
2905170000-十二醇、十六醇及十八醇
2905399099-其他二元醇
2905499000-其他多元醇
2905590090-其他无环醇的卤化、磺化等衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Yang L, Xia Y, An L, Zhou D. An LC-MS/MS method for quantification of demethylzeylasteral, a novel immunosuppressive agent in rat plasma and the application to a pharmacokinetic study. Biomed Chromatogr. 2018 Aug;32(8):e4247. doi: 10.1002/bmc.4247. Epub 2018 Apr 23. doi: 10.1002/ijc.31211. Epub 2018 Jan 4. doi: 10.1038/cddis.2017.529.
4: Zhao XM, Pu SB, Zhao QG, Gong M, Wang JB, Ma ZJ, Xiao XH, Zhao KJ. [Preliminary study on effective components of Tripterygium wilfordii for liver toxicity based on spectrum-effect correlation analysis]. Zhongguo Zhong Yao Za Zhi. 2016 Aug;41(15):2915-2921. doi: 10.4268/cjcmm20161527. Chinese. doi: 10.3892/etm.2017.4352. Epub 2017 Apr 18.
6: Wang Q, Xiao Y, Liu T, Yuan H, Li C. Demethylzeylasteral ameliorates inflammation in a rat model of unilateral ureteral obstruction through inhibiting activation of the NF κB pathway. Mol Med Rep. 2017 Jul;16(1):373-379. doi: 10.3892/mmr.2017.6584. Epub 2017 May 16.
合成参考文献
参考文献:10.1016/s0010-7824(02)00312-8
摘要:Bai JP, Shi YL. Inhibition of Ca(2+) channels in mouse spermatogenic cells by male antifertility compounds from Tripterygium wilfordii Hook. f. Contraception. 2002 Jun;65(6):441–5. doi: 10.1016/s0010-7824(02)00312-8.
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