CAS: 99-65-0; 1,3-Dinitrobenzene

上下游产品

CAS号645-00-1 1-碘-3-硝基苯 | CAS号591-18-4 1-溴-3-碘苯 | CAS号98-95-3 硝基苯 | CAS号97-02-9 2,4-二硝基苯胺 | CAS号13331-27-6 3-硝基苯硼酸 | CAS号709-49-9 2,4-二硝基碘苯 | CAS号97-00-7 1-氯-2,4-二硝基苯 | CAS号71-43-2 苯 | CAS号99-09-2 间硝基苯胺 | CAS号584-48-5 1-溴-2,4-二硝基苯 | CAS号10549-12-9 D-Phenylalanine... | CAS号1655-54-5 N-(2,4-二硝基苯基)-L-苯丙胺酸 | CAS号105112-85-4 1-nitro-3-[4-[4... | CAS号111220-32-7 2-(3-tert-butyl... | CAS号3320-87-4 3-硝基苯基异氰酸酯 | CAS号123-61-5 间苯二异氰酸酯 | CAS号350-46-9 对氟硝基苯 | CAS号34509-56-3 1,3-dinitrobenz... | CAS号3814-18-4 Benzenethiol, 3... | CAS号34126-43-7 3-硝基苯乙硫醚

📜硝基苯置于硫酸,Silica Gel,四甲基硝酸铵体系中,化学反应 0.17H,以60%的收率获得产物1,3-二硝基苯
参考文献:负载型硝酸四甲基铵/硫酸硅作为无溶剂条件下硝化芳香族化合物的有用试剂
标题:负载型硝酸四甲基铵/硫酸硅作为无溶剂条件下硝化芳香族化合物的有用试剂
摘要:摘要 使用负载型四甲基硝酸铵/硫酸硅作为一种有用的试剂,在无溶剂条件下,多种芳香族化合物被硝化为母体硝基芳香族化合物.该方法可用于活化和失活芳环的硝化.
DOI:10.1080/00397910500184685

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:WO-9817677-A1
优先权日:1996-10-24
标 题 :Improvements in solid-phase synthesis of peptides and related compounds
发明人：ENGLEBRETSEN DARREN
权利人:UNIV QUEENSLAND; ENGLEBRETSEN DARREN
摘要:The invention relates to spacers for use in solid-phase synthesis of peptides and peptide-related compounds, in which a spacer construct is used to ensure that the target peptide or peptide-related compound is at a distance equivalent to at least 5-15 amino acids from the solid support. Constructs of the invention are particularly applicable to the synthesis of strongly hydrophobic peptide, which are otherwise difficult, if not impossible to purify and analyse. The constructs and methods of the invention are also applicable to synthesis of peptide nucleic acids.

专利号:US-6770436-B1
优先权日:1996-11-14
标题:Chemical amplification for the synthesis of patterned arrays
发明人：BEECHER JODY E; GOLDBERG MARTIN J; MCGALL GLENN H
权利人:AFFYMETRIX INC
摘要:Radiation-activated catalysts (RACs), autocatalytic reactions, and protective groups are employed to achieve a highly sensitive, high resolution, radiation directed combinatorial synthesis of pattern arrays of diverse polymers. When irradiated, RACs produce catalysts that can react with enhancers, such as those involved in autocatalytic reactions. The autocatalytic reactions produce at least one product that removes protecting groups from synthesis intermediates. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.

专利号:US-10751419-B2
优先权日:2014-05-01
标题:Method for synthesis of reactive conjugate clusters
发明人：MIGAWA MICHAEL T; YU JINGHUA; WAN W BRAD; PATEL SAYTEN P; VASQUEZ GUILLERMO; KINBERGER GARTH A; PRAKASH THAZHA P; SETH PUNIT P; SWAYZE ERIC E
权利人:IONIS PHARMACEUTICALS INC
摘要:Provided herein are improved methods for the synthesis of reactive conjugate clusters and intermediates used in such methods. In particular, improvements are provided that enhance the synthesis of reactive conjugate clusters by reducing the number of synthetic steps required. The reactive conjugate clusters prepared using the improved methods don't include any transacylation impurities that are formed using existing methods. The improved methods also provide an increase in overall yield and a cost benefit over existing methods.

专利号:US-8318427-B2
优先权日:2005-12-29
标 题 :Use of acid scavengers for the synthesis of standard length and long-mer nucleic acid arrays
发明人：KUIMELIS ROBERT G; MCGALL GLENN H; GOLDBERG MARTIN J; XU GUANGYU
权利人:KUIMELIS ROBERT G; MCGALL GLENN H; GOLDBERG MARTIN J; XU GUANGYU; AFFYMETRIX INC
摘要:Protective groups which may be cleaved with an activatable deprotecting reagents are employed to achieve a highly sensitive, high resolution, combinatorial synthesis of pattern arrays of diverse polymers. In preferred embodiments of the instant invention, the activatable deprotecting reagent is a photoacid generator and the protective groups are DMT for nucleic acids and tBOC for amino acids. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.