CAS: 75-38-7; 1,1-Difluoroethylene

主要参考文献

参考标题:Cross-Metathesis Reaction Of Functionalized And Substituted Olefins Using Group 8 Transition Metal Carbene Complexes As Metathesis Catalysts
摘要:The Invention Pertains To The Use Of Group 8 Transition Metal Carbene Complexes As Catalysts For Olefin Cross-Metathesis Reactions. In Particular, Ruthenium And Osmium Alkylidene Complexes Substituted With An N-Heterocyclic Carbene Ligand Are Used To Catalyze Cross-Metathesis Reactions To Provide A Variety Of Substituted And Functionalized Olefins, Including Phosphonate-Substituted Olefins, Directly Halogenated Olefins, 1,1,2-Trisubstituted Olefins, And Quaternary Allylic Olefins. The Invention Further Provides A Method For Creating Functional Diversity Using The Aforementioned Complexes To Catalyze Cross-Metathesis Reactions Of A First Olefinic Reactant, Which May Or May Not Be Substituted With A Functional Group, With Each Of A Plurality Of Different Olefinic Reactants, Which May Or May Not Be Substituted With Functional Groups, To Give A Plurality Of Structurally Distinct Olefinic Products. The Methodology Of The Invention Is Also Useful In Facilitating The Stereoselective Synthesis Of 1,2-Disubstituted Olefins In The Cis Configuration.

合成参考文献

参考DOI号:10.1016/S0040-4039(02)01952-4