CAS: 63492-69-3; (Z)-2-((4R,5S,6S)-4,5-Dihydroxy-6-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Cyclohex-2-En-1-Ylidene)Acetonitrile

上下游产品

CAS号561023-24-3 (2E)-{(4R,5S,6S...

📜(2Z)-{(4R,5S,6S)-4,5-Diacetoxy-6-[(2,3,4,6-Tetra-O-Acetyl-β-D-Glucopyranosyl)Oxy]Cyclohex-2-En-1-Ylidene}Acetonitrile置于sodium Methylate体系中,用 甲醇 作为反应溶剂,化学反应 1.0H,以93%的收率获得产物紫草氰苷
参考文献:(-)-紫草精苷的全合成†
标题:(-)-紫草精苷的全合成†
摘要:天然存在的非氰基氰基葡萄糖苷(-)-锂精子苷(1)的合成是从光学纯的oxatrinorbornenoneone(+)-2开始,共分12步完成,总收率为10%.合成的关键步骤糖苷化对空间位阻非常敏感,因此,我们必须优化对糖苷配基的其他两个oh功能所用保护剂的选择.最终,在koenigs-Knorr-糖苷化条件下,以与全合成(-)-紫胶苷密切相关的条件,以非常高的收率(72%)获得了所需的β-D-葡萄糖苷15.
DOI:10.1002/hlca.200390065

专利信息

专利号:US-7799932-B2
优先权日:2005-10-06
标 题:N-substituted 3,4-alkylenedioxypyrroles, ester substituted dihydroxypyrroles and methods for synthesis of these pyrroles
发明人：REYNOLDS JOHN R; WALCZAK RYAN M; COWART II JOHN SIGURE
权利人:UNIV FLORIDA
摘要:A family of N-substituted 3,4-alkylenedioxypyrrole includes monomers for of formula (I) electropolymerization to conjugated polymers and key intermediates for the preparation of the monomers. The preparation of the //-substituted 3,4-alkylenedioxypyrroles is carried out via a synthetic intermediate, an ester substituted dihydroxypyrrole. The synthetic method to prepare the //-substituted 3,4-alkylenedioxypyrrole intermediates and ultimately the N-substituted 3,4-alkylenedioxypyrrole monomers begins with a reaction to form the ester substituted dihydroxypyrrole.

专利号:US-2009149661-A1
优先权日:2005-10-06
标题 :N-Substituted 3,4-Alkylenedioxypyrroles, Ester Substituted Dihydroxypyrroles and Methods for Synthesis of These Pyrroles

专利号:EP-1931630-B1
优先权日:2005-10-06
标 题 :N-substituted 3,4-alkylenedioxypyrroles, ester substituted dihydroxypyrroles and methods for synthesis of these pyrroles