CAS: 60479-65-4; (S)-2-(Dibenzylamino)Propan-1-Ol

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CAS号87281-16-1 2-dibenzylamino... | CAS号111060-49-2 (S)-2-dibenzyla... | CAS号2749-11-3 L-氨基丙醇 | CAS号100-39-0 溴化苄 | CAS号100-44-7 氯化苄

合成工艺路线路线简述

  • 合成目标产物 (S)-(+)-2-(Dibenzylamino)-1-Propanol 主要起始原料 L-Alaninol And Benzyl Bromide
  • (文献来源)合成步骤主要原料 L-Alaninol 和 Benzyl Bromide
📜溴甲苯置于lithium Aluminium Tetrahydride,Potassium Carbonate,Sodium Hydroxide体系中,用 乙醚,水 作为反应溶剂,化学反应生成 (S)-(+)-2-(二苄氨基)-1-丙醇
参考文献:Khmds/triglyme Cryptate As An Alternative To Phosphazene Base In Stereodivergent Pentafluoroethylation Of N-Sulfinylimines Using Hfc-125
标题:Khmds/triglyme Cryptate As An Alternative To Phosphazene Base In Stereodivergent Pentafluoroethylation Of N-Sulfinylimines Using Hfc-125
摘要:
DOI:10.1021/acs.Joc.2C01821

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专利信息


专利号:US-9446995-B2
优先权日:2012-05-21
标 题:Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
发明人:CHONG HYUN-SOON
权利人:CHONG HYUN-SOON; ILLINOIS INST OF TECH
摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

专利号:US-2017008863-A1
优先权日:2008-02-22
标 题:Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions

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✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Synthetic And Theoretical Investigation On The One-Pot Halogenation Of β-Amino Alcohols And Nucleophilic Ring Opening Of Aziridinium Ions
作者:Yunwei Chen,Xiang Sun,Ningjie Wu,Jingbai Li,Shengnan Jin,Yongliang Zhong,Zirui Liu,Andrey Rogachev,Hyun-Soon Chong
摘要:Aziridinium Ions Are Useful Reactive Intermediates For The Synthesis Of Enantiomerically Enriched Building Blocks. However, N,N-Dialkyl Aziridinium Ions Are Relatively Underutilized In The Synthesis Of Optically Active Molecules As Compared To Other Three-Membered Ring Cogeners, Aziridines And Epoxides. The Characterization Of Both Optically Active Aziridinium Ions And Secondary β-Halo Amines As The

合成参考文献


摘要:Dax, K., Science of Synthesis, (2005) 34, 108.
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