CAS: 593-96-4; 1-Bromo-1-Chloroethane

该化合物是一种卤化有机化合物,其特点是在乙烷主干柱中含有与同一碳原子相连的溴和氯原子;该化合物一般是一种无色液体,有甜味,以其挥发性闻名;它具有相对较低的沸点,在有机溶剂中可溶解,使其在各种化学应用中有用;卤素在其结构中的存在可产生回动性,使其能参与核循环替代反应,这在有机合成中是常见的;此外,1-溴-1-氯乙烷可作为中间体用于生产其他化学品,并可作为实验室环境中的溶剂或试剂;然而,由于卤化化合物对环境和健康的潜在影响,适当的处理和处置措施至关重要.

结构式图片

相似化合物

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CAS号5813-64-9 新戊胺 | CAS号122-39-4 二苯胺 | CAS号75-01-4 乙烯基氯 | CAS号27816-36-0 2-氯丙酰胺 | CAS号74-84-0 乙烷 | CAS号74-96-4 溴乙烷 | CAS号75-00-3 氯乙烷 | CAS号74-97-5 溴氯甲烷 | CAS号74-88-4 碘甲烷 | CAS号106004-06-2 1-(2-氯乙基)环己烷-1,... | CAS号593-60-2 溴乙烯 | CAS号75-34-3 1,1-二氯乙烷标准溶液 | CAS号557-91-5 1,1-二溴乙烷 | CAS号75-01-4 乙烯基氯 | CAS号1615-75-4 1-氯-1-氟乙烷 | CAS号13557-25-0 1-chloroethylsu... | CAS号5912-58-3 alpha-氯乙基乙酸酯 | CAS号594-02-5 1,1-Diiodoethane | CAS号40258-80-8 1-chloroethyl p...

合成工艺路线路线简述

    📜氯乙烯置于氢溴酸,Thio-P-Cresol体系中,化学反应生成 1-溴-1-氯乙烷
    参考文献:Kharasch; Kleiger; Mayo,Journal Of Organic Chemistry,1939,Vol. 4,P. 431,434
    标题:Kharasch; Kleiger; Mayo,Journal Of Organic Chemistry,1939,Vol. 4,P. 431,434

    海关参考信息

    专利信息


    专利号:WO-2019016826-A1
    优先权日:2017-07-17
    标 题:NOVEL 5- [4- (2-BIPHENYL-4-YL-2-OXOETHOXY) BENZYLIDENE] THIAZOLIDINE-2,4-DIONES, THEIR SYNTHESIS AND USES THEREOF
    发明人:THAREJA SURESH; VERMA SANT KUMAR; JAIN AKHLESH KUMAR; BHARDWAJ TILAK RAJ
    权利人:GURU GHASIDAS VISHWAVIDYALAYA A CENTRAL UNIV; INDIAN COUNCIL OF MEDICAL RES ICMR
    摘要:Disclosed are novel 5-[4-(2-biphenyl-4-yl-2-oxo-ethoxy)-benzylidene]-thiazolidine-2,4-dione compounds of general formula (I), their pharmaceutically acceptable salts, solvates their synthesis and uses thereof, to pharmaceutical compositions containing compounds and to the use of such compounds and composition in medicines either alone or in combination with other compounds.

    专利号:WO-2011029896-A1
    优先权日:2009-09-11
    标 题 :Methods of preparation of muscarinic acetylcholine receptor antagonists
    发明人:CARANGIO ANTONELLA; CHEUNG IZABEL; D SOUZA ERIN CARMEN FRANCES; LEAHY JOHN HENRY; STRACHAN JOHN BRYCE
    权利人:GLAXO GROUP LTD; CARANGIO ANTONELLA; CHEUNG IZABEL; D SOUZA ERIN CARMEN FRANCES; LEAHY JOHN HENRY; STRACHAN JOHN BRYCE
    摘要:The present application describes novel intermediates useful in the synthesis of mAChRs and methods for preparing these intermediates, comprising a compound of Formula (II): wherein, P is a suitably nitrogen protecting group; R is selected from the group consisting of C 1 - 8 alkyl, C 2 - 8 alkenyl, C 2 - 8 alkynyl, C 3 - 6 cycloalkyl, C 3 - 6 cycloalkenyl, heterocyclic, heterocyclic C 1 - 4 alkyl, aryl, aryl C 1 - 4 alkyl and heteroaryl C 1 - 4 alkyl; and Y is a suitable leaving group.

    专利号:US-4150032-A
    优先权日:1978-01-18
    标 题 :9-Oxobenzomorphan process and intermediates
    发明人:KAVADIAS GERRY
    权利人:BRISTOL MYERS CO
    摘要:Improved processes for preparing 2'-alkoxy-2,5-di-substituted-9-oxo-6,7-benzomorphans from benz[e]indolines and synthesis of the benz[e]indoline intermediates are described. A representative example involves synthesis of 9b-allyl-8-methoxy-3-methyl-5,9b-dihydrobenz[e]indoline and bromination thereof to 9b-allyl-4-bromo-8-methoxy-2,4,5,9b-tetrahydro-1H-benz[e]indole methylbromide which is then hydrolyzed with a weak base such as ammonium bicarbonate to provide 5-allyl-2'-methoxy-2-methyl-9-oxo-6,7-benzomorphan.

    专利号:US-4234731-A
    优先权日:1979-01-05
    标题:9-Oxobenzomorphan process
    发明人:KAVADIAS GERRY
    权利人:BRISTOL MYERS CO
    摘要:Improved processes for preparing 2'-alkoxy-2,5-di-substituted-9-oxo-6,7-benzomorphans from benz[e]indolines and synthesis of the benz[e]indoline intermediates are described. A representative example involves synthesis of 9b-allyl-8-methoxy-3-methyl-5,9b-dihydrobenz[e]indoline and bromination thereof to 9b-allyl-4-bromo-8-methoxy-2,4,5,9b-tetrahydro-1H-benz[e]indole methylbromide which is then hydrolyzed with a weak base such as ammonium bicarbonate to provide 5-allyl-2'-methoxy-2-methyl-9-oxo-6,7-benzomorphan.

    专利号:US-6011133-A
    优先权日:1993-03-05
    标 题:Laminates of glass or metal and poly(alkylene dicarboxylates) and syntheses thereof
    发明人:PINKUS ALVIN G; HARIHARAN RAJAN
    权利人:UNIV BAYLOR
    摘要:Poly(alkylene dicarboxylate) polymers and copolymers having tetraalkyl- or trialkylammonium ion end groups and methods of synthesis, thereof. The methylene-containing copolymers, in general, adhere to glass and metals, including aluminum, iron, and copper. Poly(methylene-co-ethylene terephthalate) is a clear film useful in the protection of metals or glass from corrosion or scratching. Glass may be bound to glass or to metal using the polymers of the present invention or metal to metal seals may be made.

    专利号:US-9018325-B2
    优先权日:2011-08-25
    标题 :Catalyst for living radical polymerization and polymerization method
    发明人:GOTO ATSUSHI; KAJI HIRONORI
    权利人:GOTO ATSUSHI; KAJI HIRONORI; UNIV KYOTO
    摘要:A nonmetallic compound having an ionic bond with a halide ion is used as a catalyst for living radical polymerization. Even if a radical initiator is not used, a monomer can be subjected to a radical polymerization to obtain a polymer having narrow molecular weight distribution. The cost of the living radical polymerization can be remarkably reduced, and it is made possible to prevent adverse effects of using a radical initiator (such as side reactions). The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages such as low toxicity of the catalyst, low amount of the catalyst necessary, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor, etc. The catalyst can be applied to various monomers and enables synthesis of high molecular weight polymers.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s00203-024-04105-1
    摘要:Verma H, Kaur J, Thakur V, Dhingra GG, Lal R. Comprehensive review on Haloalkane dehalogenase (LinB): a β-hexachlorocyclohexane (HCH) degrading enzyme. Arch Microbiol. 2024 Aug 14;206(9):380. doi: 10.1007/s00203-024-04105-1.
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