CAS: 543-67-9; Propyl Nitrite

上下游产品

propan-1-ol propyl bromide 1-iodo-propane propyloxyldi-1-propyl sulfate propylamine propionaldehyde formaldehyd

📜Propyloxyl置于氧化亚氮体系中,289.0 °C,13.33 Kpa 条件下,反应生成 亚硝酸丙酯
参考文献:Rate Constants For The Reactions Of C2H5O,I-C3H7O,And N-C3H7O With No And O2 As A Function Of Temperature
标题:Rate Constants For The Reactions Of C2H5O,I-C3H7O,And N-C3H7O With No And O2 As A Function Of Temperature
摘要:The Rate Constants Of The Reactions Of Ethoxy (C2H5O),I-Propoxy (I-C3H7O) And N-Propoxy (N-C3H7O) Radicals With O-2 And No Have Been Measured As A Function Of Temperature. Radicals Have Been Generated By Laser Photolysis From The Appropriate Alkyl Nitrite And Have Been Detected By Laser-Induced Fluorescence. The Following Arrhenius Expressions Have Been Determined:(R-1) C2H5O + O-2--> Products K(1) = (2.4 +/-0.9) X 10(-14) Exp(-2.7 +/-1.0 Kjmol(-1)/rt) Cm(3) S(-1) 295K < T < 354K P = 100 Torr(R-2) I-C3H7O + O-2--> Products K(2) = (1.6 +/-0.2) X 10(-14) Exp(-2.2 +/-0.2 Kjmol(-1)/rt) Cm(3) S(-1) 288K < T < 364K P = 50-200 Torr(R-3) N-C3H7O + O-2--> Products K(3) = (2.5 +/-0.5) X 10(-14) Exp(-2.0 +/-0.5 Kjmol(-1)/rt) Cm(3) S(-1) 289K < T < 381K P = 30-100 Torr(R-4) C2H5O + No--> Products K(4) = (2.0 +/-0.7) X 10(-11) Exp(0.6 +/-0.4 Kjmol(-1)/rt) Cm(3) S(-1) 286K < T < 388K P = 30-500 Torr(R-5) I-C3H7O + No--> Products K(5) = (8.9 +/-0.21 X 10(-12) Exp(3.3 +/-0.5 Kjmol(-1)/rt) Cm(3) S(-1) 286K < T < 389K P = 30-500 Torr(R-6) N-C3H7O + No--> Products K(6) = (1.2 +/-0.2) X 10(-11) Exp(2.9 +/-0.4 Kjmol(-1)/rt) Cm(3)S(-1) 289K < T < 380K P = 30-100 Torrall Reactions Have Been Found Independent Of Total Pressure Between 30 And 500 Torr Within The Experimental Error. (C) 1999 John Wiley & Sons,Inc.
DOI:10.1002/(Sici)1097-4601(1999)31:12<860::Aid-Kin4>3.0.Co;2-E

专利信息

专利号:US-7452994-B2
优先权日:2001-09-12
标 题 :Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
发明人：MCEACHERN ERNEST J; BRIDGER GARY J; SKUPINSKA KRYSTYNA A; SKERLJ RENATO T; YANG WEN
权利人:ANORMED INC
摘要:This invention describes various processes for synthesis and resolution of racemic amino-substituted fused bicyclic ring systems. One process utilizes selective hydrogenation of an amino-substituted fused bicyclic aromatic ring system. An alternative process prepares the racemic amino-substituted fused bicyclic ring system via nitrosation. In addition, the present invention describes the enzymatic resolution of a racemic mixture to produce the (R)- and (S)-forms of amino-substituted fused bicyclic rings as well as a racemization process to recycle the unpreferred enantioner. Further provided by this invention is an asymmetric synthesis of the (R)- or (S)-enantiomer of primary amino-substituted fused bicyclic ring systems.

专利号:US-11649213-B2
优先权日:2018-09-26
标题 :Synthetic method for the preparation of a 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol compound
发明人：MEISENBACH MARK; MARTIN BENJAMIN; RONDE NIEK JOHANNES; RUIZ CARMEN
权利人:MEREO BIOPHARMA 1 LTD
摘要:Provided is a process for preparing a compound, comprising the steps of a) Reacting a compound of Formula A (Formula A) with the compound 3 (3) to provide the compound 5 (5) or a salt or solvate thereof, wherein R is a linear or branched C1-C5 alkyl. Further provided is the compound 5 or a salt or solvate thereof. (5) The use of these compounds in the synthesis of 3-[5-Amino-4-(3-Cyanobenzoyl)-Pyrazol-1-yl]-N-Cyclopropyl-4-Methylbenzamide is also provided.

专利号:US-3697597-A
优先权日:1968-09-21
标 题:Process for the preparation of alpha-oximinoalkyl ketones
发明人：DORLARS ALFONS
权利人:BAYER AG
摘要:Alpha -Oximino ketones, for example, oximinodipropyl ketone, are prepared by reacting a ketone in an inert organic solvent immiscible with water in the presence of a hydrogen halide with an amount of alkyl nitrite that is insufficient for complete nitrosation followed by extracting the ketone formed with an aqueous alkali solution, removing the alkaline extract formed and isolating the Alpha -oximino ketone. The ketones formed are useful as intermediates in the synthesis of pharmaceutical compounds, dyes, analytical reagents, plant protection agents, and optical brighteners.

专利号:US-9181203-B2
优先权日:2010-11-12
标题:Substituted pyrazino[2,3-d]isooxazoles as intermediates for the synthesis of substituted pyrazinecarbonitriles and substituted pyrazinecarboxamides
发明人：NAKAMURA KOUKI; MURAKAMI TAKESHI; NAITOU HIROYUKI; HANAKI NAOYUKI; WATANABE KATSUYUKI
权利人:FUJIFILM CORP; TOYAMA CHEMICAL CO LTD
摘要:The object of the present invention is to provide a compound which is useful as a production intermediate of pyrazine carboxamide derivative such as 6-fluoro-3-hydroxy-2-pyrazine carboxamide. The present invention provides a pyrazino[2,3-d]isoxazole derivative represented by the formula (I): n nwherein X represents a halogen atom, a hydroxyl group or a sulfamoyloxy group, and Y represents —C(â•?O)R or —CN; wherein R represents a hydrogen atom, an alkoxy group an aryloxy group, an alkyl group, an aryl group or an amino group.

专利号:US-2003114679-A1
优先权日:2001-09-12
标 题:Synthesis of enantiomerically pure amino-substituted fused bicyclic rings

专利号:US-2005080267-A1
优先权日:2001-09-12
标 题:Synthesis of enantiomerically pure amino-substituted fused bicyclic rings