CAS: 52663-77-1; 2,2',3,3',4,5,5',6,6'-Nonachlorobiphenyl
该化合物是多氯联苯(PCB)家族的成员,该家族由以其环境持久性和潜在毒性而闻名的合成有机化学品组成.PCB 208的特点是结构复杂,含有联苯所附带的多种氯原子,有助于其化学稳定性和疏水性.该化合物的浓度和配方一般不光黄色固体或粘粘液,无色,无光黄色固体或粘粘液.PC PC 208以其高热稳定性和耐降解性闻名,在各种工业用途,如电气设备和热传导液中有用.然而,由于其环境持久性和生物累积潜力,PCB 208具有重大的生态和健康风险,包括内分泌干扰和致癌影响.许多国家已实施管制措施,限制多氯联苯(包括PC 208)的使用和释放到环境中,反映出人们对其长期影响人类健康和生态系统的关切日益增强.
- 英文名称2,2',3,3',4,5,5',6,6'-Nonachlorobiphenyl
- 中文名称2,2',3,3',4,5,5',6,6'-九氯联苯
- IUPAC名称1,2,3,4,5-pentachloro-6-(2,3,5,6-tetrachlorophenyl)benzene
- 其它别名2,2',3,3',4,5,5',6,6'-Nonachlorobiphenyl; 2,3,4,5,6,2',3',5',6'-Nonachlorobiphenyl
- CAS编号52663-77-1
- MFCD编号:MFCD00152676
- FDA UNII编号:9F764L5V9Z
- 分子式:C12HCl9分子量:464.21
- 产品CID: 2496366
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
pentachlorobenzene 2,3,5,6-tetrachloroaniline合成工艺路线路线简述
📜五氯苯,2,3,5,6-四氯苯胺置于亚硝酸异戊酯体系中,化学反应生成 2,2',3,3',4,5,5',6,6'-九氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:S116 | REFCCS | Collision Cross Section (CCS) Values from Literature | DOI:10.5281/zenodo.10932895
摘要:S50 | CCSCOMPEND | The Unified Collision Cross Section (CCS) Compendium | DOI:10.5281/zenodo.2658162
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). http://www.atsdr.cdc.gov/mrls/
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