CAS: 51-26-3; 3,3',5-Triiodo Thyropropionic Acid
该化合物是一种合成甲状腺激素模拟物,其特征是三碘化结构,具有独特的生化特性.该化合物主要用于研究研究甲状腺激素新陈代谢,受体相互作用和代谢途径. 它与内生甲状腺激素结构相似,因此可以作为研究激素信号机制的宝贵工具. 3,3',5和5位置的碘原子的存在增强了其稳定性和约束性,使其适合于需要精确调节甲状腺相关过程的实验研究. 研究人员认为该化合物在体外和活性模型中具有再生性和实用性.
- ⚠️《化妆品禁用原料目录》
- 英文名称3,3',5-Triiodo Thyropropionic Acid
- 中文名称去氨甲碘安
- IUPAC名称3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid
- 其它别名Hydr°Cinnamicacid, 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo- (6CI,8CI); 3,3',5-Triiodothyropropionic acid; 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodohydr°Cinnamic acid; Atralose; Birodan; Thyropropic acid; Triopron; Triprop; [(4-Hydroxy-3-iodo-4-phenoxy)-3,5-diiodophenyl]propionic acid; b-[4-(3'-Iodo-4'-hydroxyphenoxy)-3,5-diiodophenyl]propionicacid
- CAS编号51-26-3
- MFCD编号:MFCD00055828
- FDA UNII编号:OK7481S22O
- 分子式:C15H11I3O4分子量:635.96
- 产品CID: 1501752
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
物理性质
MSDS等安全信息
上下游产品
3-[4-(4-hydroxy-phenoxy)-3,5-diiodo-phenyl]-propionic acid -propan-1-ol3-4-(4-Hydroxy-3-iod-phenoxy)-3,5-diiod-phenyl-propan-1-ol合成工艺路线路线简述
📜3-[4-(4-羟基苯氧基)-3,5-二碘苯基]丙酸置于氨,碘体系中,用 甲醇,水 作为反应溶剂,化学反应 0.25H,反应生成 去氨甲碘安
参考文献:Method To Treat Chronic Heart Failure And/or Elevated Cholesterol Levels
标题:Method To Treat Chronic Heart Failure And/or Elevated Cholesterol Levels
摘要:通过给患有充血性心力衰竭的患者施用治疗有效量的3',3,5-三碘甲状腺丙酸(triprop)或3,5,3',5'-四碘甲状腺丙酸(tetraprop)的方法.还描述了通过给患者施用治疗有效量的triprop或tetraprop来降低胆固醇血液水平的方法.
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications
专利号:AU-2007308022-B2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
