CAS: 40635-11-8; 6,7-Dichloroquinoline

该化合物是一种卤化的奎宁衍生物,配有分子式C9H5Cl2N. 这种环形化合物的特点是,在奎诺林环的6和7个位置上存在氯原子,这增强了其在有机合成中的回作用和效用;它是制药,农用化学品和特殊化学品的制作的多用途中间体;二氯替代模式具有不同的电子特性,对建造复杂的分子结构很有价值;其稳定性和与各种反应条件的兼容性进一步有助于其在研究和工业应用中广泛使用氯原子;建议适当处理和储存,因为其具有潜在的回性.

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612-61-3 612-57-7 4203-18-3

上下游产品

CAS号56-81-5 甘油 | CAS号95-76-1 3,4-二氯苯胺 | CAS号333383-84-9 N-(3,4-dichloro... | CAS号17847-44-8 N-Methansulfony...

合成工艺路线路线简述

    📜甲磺酰胺,N-(3,4-二氯苯基)-置于三氟甲磺酸,三乙胺体系中,用 甲醇,二氯甲烷 作为反应溶剂,化学反应 0.17H,反应生成 6,7-二氯喹啉
    参考文献:Tokuyama,Hidetoshi; Sato,Masashi; Ueda,Toshihiro,Heterocycles,2001,Vol. 54,# 1,P. 105-108
    标题:Tokuyama,Hidetoshi; Sato,Masashi; Ueda,Toshihiro,Heterocycles,2001,Vol. 54,# 1,P. 105-108

    海关参考信息

    专利信息


    专利号:US-7897774-B2
    优先权日:2005-03-03
    标题:Cyclic compound having quinolylalkylthio group
    发明人:KAWASHIMA KENJI; HONDA TAKAHIRO; TAJIMA HISASHI; OKAMOTO KAZUYOSHI; YAMAMOTO MINORU
    权利人:SANTEN PHARMACEUTICAL CO LTD
    摘要:The present invention relates to a synthesis study of novel cyclic compounds having a quinolylalkylthio group represented by the formula (1), and pharmacological actions of the compounds. n nIn the formula, the ring X represents:n n nwhich may have halogen and/or alkyl; R 1 and R 2 independently represent hydrogen, alkyl, cycloalkyl, aryl or a (non) aromatic heterocycle; R 3 represents qinolyl; A represents sulfur, sulfinyl or sulfonyl; and B represents alkylene.

    专利号:EP-1465880-B1
    优先权日:2001-11-28
    标题 :5-sulphanyl-4h-1,2,4-triazole derivatives and their use to treat disorders associated with somatostatine
    发明人:GALCERA CONTOUR MARIE-ODILE; SIDHU ALBAN; ROUBERT PIERRE; THURIEAU CHRISTOPHE
    权利人:IPSEN PHARMA
    摘要:The invention concerns novel 5-sulphanyl-4H-1,2,4-triazole derivatives of formula (I), wherein: R1, R2 and R3 represent variable groups and the methods for preparing them by liquid-phase parallel synthesis processes. Said product exhibit good affinity for certain sub-types of somatostatin receptors; they are particularly useful for treating pathological conditions or diseases wherein one (or more) somatostatin receptors is (are) involved. The invention also concerns pharmaceutical compositions containing said products and their use for preparing a medicine.

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