CAS: 3639-21-2; 2-Ethyl-2-Hydroxybutanoic Acid

该化合物是一种分支链式氢氧化酸,其特点是独特的结构特征,结合了氢氧基和碳化物功能组.该化合物展示了多功能性,在有机合成中具有价值,特别是对于培养酯,乳腺和其他衍生物而言.其分支烷基链增加了有机溶剂的溶解性,而氢氧基组则提供了进一步实现功能化的机会.分子在中度条件下的稳定性及其与各种反应路径的兼容性使它成为制药,农用化学品和特殊化学物的有用中间体.由于箱酸具有典型的潜在刺激性,因此建议谨慎处理.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号75-03-6 碘乙烷 | CAS号95-92-1 草酸二乙酯 | CAS号553-90-2 草酸二甲酯 | CAS号34451-66-6 2-乙基-2-羟基丁腈 | CAS号74-90-8 氢氰酸 | CAS号96-22-0 3-戊酮 | CAS号105-37-3 丙酸乙酯 | CAS号511-70-6 2-溴-2-乙基丁酰胺 | CAS号5456-23-5 2-溴-2-乙基丁酸 | CAS号861534-39-6 N,N'-bis-(2-eth... | CAS号96-22-0 3-戊酮 | CAS号4411-99-8 2-ethyl-2-buten... | CAS号1187-13-9 2-Ethylcrotonic acid | CAS号66553-16-0 2-ethylbutane-1... | CAS号34452-15-8 2-ethyl-cis-cro... | CAS号5582-86-5 2-乙基-2-羟基丁酸乙酯

合成工艺路线路线简述

    📜丙酸乙酯置于sodium Bromate,Sodium体系中,化学反应生成2-乙基-2-羟基丁酸
    参考文献:One-Flask Preparation Of Symmetrical Ketones And 1,2-Diketones From Esters
    标题:One-Flask Preparation Of Symmetrical Ketones And 1,2-Diketones From Esters
    摘要:据报道,利用钠金属诱导的酰化醇缩合反应,随后与亚硫酰氯反应,可以方便地在一瓶中制备一系列对称型1,2-二酮.当初步的酰化醇缩合反应完成后,通过与水合次溴酸钠氧化,再与亚硫酰氯反应,可以获得对称的一元酮.本文讨论了制备方面的细节,反应的应用范围以及提出的反应机制.
    Doi:10.1055/s-1991-28415

    海关参考信息

    专利信息


    专利号:EP-0548237-B1
    优先权日:1990-09-10
    标 题:Method for the production of an article from the Copolymer of Lactide and (e)-Caprolactone for medical applications
    发明人:GRIJPMA DIRK WYBE; PENNINGS ALBERT JOHAN
    权利人:UNIV GRONINGEN
    摘要:The invention relates to a method for the production of an article from a copolymer of lactide and epsilon -caprolactone for medical applications, in which method the copolymer is obtained by a synthesis which is carried out as a bulk synthesis at a temperature of 80 to 160 DEG C. Articles according to the invention can be used in numerous fields, but are in particular advantageous if they are employed in biomedical fields. Examples are an implant for the repair of a meniscus or a blood vessel, stents or artificial skin. Stents are small spirals which are used to hold open (coronary) arteries which have silted up. Use in abdominal wall reconstruction is also possible.

    专利号:EP-3661901-B1
    优先权日:2017-08-02
    标 题:Synthesis of glycols via transfer hydrogenation of alpha-functional esters with alcohols

    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

    专利号:US-7196230-B2
    优先权日:2002-03-11
    标 题 :Phosoxophite ligands and use thereof in carbonylation processes
    发明人:PENG WEI-JUN; BRYANT DAVID ROBERT
    权利人:UNION CARBIDE CHEM PLASTIC
    摘要:A novel organophosphorus composition and synthesis thereof, the composition being characterized by one phosphite moiety, one phosoxophite moiety, and a plurality of sterically bulky substituents. The novel composition finds utility as a ligand in Group VIII transition metal phosoxophite complex catalysts and complex catalyst precursors that are used in carbonylation processes, preferably, hydroformylation processes. Additionally, there is disclosed a novel method of preparing a phosphoromonochloridite composition that finds utility as a precursor to the novel phosoxophite composition.

    专利号:RU-2176645-C2
    优先权日:1995-07-06
    标 题:Thrombin inhibitors, pharmaceutical composition based on thereof, method of treatment, method of their synthesis (versions) and protected derivative

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s12035-024-04429-5
    摘要:Baghel R, Maan K, Dhariwal S, Kumari M, Sharma A, Manda K, Trivedi R, Rana P. Mild Blast Exposure Dysregulates Metabolic Pathways and Correlation Networking as Evident from LC-MS-Based Plasma Profiling. Mol Neurobiol. 2025 Mar;62(3):3143–66. doi: 10.1007/s12035-024-04429-5.
    参考文献:10.1186/s12870-025-06340-0
    摘要:Liu Y, Ling W, Li Y, Zhou Y, Li J, Chen S, Zhou J, Yang F. Inoculation of Lactobacillus parafarraginis enhances silage quality, microbial community structure, and metabolic profiles in hybrid Pennisetum. BMC Plant Biol. 2025 Mar 13;25(1):325.
    参考文献:10.1007/s12011-025-04641-x
    摘要:Marchi S, Repke K, Sunde G, Wilkes E, Kovitch K, McMillan R, Stallings D, Vincent JB, Woski SA. Do Ternary DNA-Cr(III)-Small Molecule Adducts Form Biol Trace Elem Res. 2025 May 01;203(12):6292–309. doi: 10.1007/s12011-025-04641-x.
    参考文献:10.1186/s12866-025-04009-0
    摘要:Hong G, Zhao Y, Zhou J, Hu L, Li G, Jin Y. Circadian rhythm perturbation causes IBS-like characteristics and altered fecal metabolome in mice. BMC Microbiol. 2025 May 07;25(1):274.
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