专利号:CN-204365127-U 优先权日:2014-12-27 标 题:A kind of hydrogen chloride tail gas treating apparatus being used for the synthesis of 3,4-bis-chlorobenzotrifluoride
专利号:KR-20180074695-A 优先权日:2015-10-26 标题 :Synthesis of 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acid
专利号:KR-102734783-B1 优先权日:2015-10-26 标 题:Method for the synthesis of 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acid
专利号:US-8648203-B2 优先权日:2005-11-23 标 题:Process for preparing pyridinamines and novel polymorphs thereof 发明人:COHEN SHLOMI; ZAMIR SHARONA 权利人:COHEN SHLOMI; ZAMIR SHARONA; MAKHTESHIM CHEM WORKS LTD 摘要:The present invention relates to an improved process for the synthesis and purification of 3-chloro-N-(3-chloro-5-tri-fluoromethyl-2-pyridyl)-α,α,α-trifluoro-2,6-di-nitro-p-toluidine (fluazinam) and other pyridinamines, which implements methyl isobutyl ketone (MIBK) as the reaction solvent. The process of the invention overcomes the drawbacks of prior art methods, by reducing the side reactions such as hydrolysis, eliminating the need for difficult and labor-intensive purification methods, and providing pure products in higher yields. The present invention relates to novel crystalline polymorphic forms fluazinam, and to mixtures of the polymorphs. The present invention also provides methods for preparing the novel polymorphs, as well as pharmaceutical compositions comprising same, and methods of using the polymorphs as pesticidal agents for combating noxious living organisms on agricultural and horticultural crops.
专利号:CN-116986994-A 优先权日:2023-08-03 标题 :Synthesis method of o-aminotrifluorotoluene
专利号:CN-113861242-B 优先权日:2021-10-29 标题:A kind of synthesis method of caged phosphonate
[参考文献]: M P Yurawecz, Et Al. Gas-Liquid Chromatographic And Mass Spectrometric Indentification Of Chlorinated Trifluorotoluene Residues In Niagara River Fish. J Assoc Off Anal Chem. 1979 Jan;62(1):36-40.
合成参考文献
摘要:National Technical Information Service., OTS0537054