CAS: 13726-69-7; Boc-Hyp-Oh

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CAS号24424-99-5 二碳酸二叔丁酯 | CAS号51-35-4 L-羟脯氨酸 | CAS号34619-03-9 碳酸二叔丁酯 | CAS号184046-78-4 (2S,3S)-3-羟基-1,... | CAS号74844-91-0 N-B°C-反式-4-羟基-L... | CAS号7732-18-5 水 | CAS号3236-56-4 dipercarbonate ... | CAS号115352-39-1 (2R)-1-benzylox... | CAS号84348-37-8 N-B°C-4-氧代-L-脯氨酸 | CAS号87691-27-8 N-B°C-顺式-4-羟基-L-脯氨酸 | CAS号364750-80-1 (2S,4R)-1-(叔丁氧羰... | CAS号148017-43-0 (2S,4S)-4-(乙酰硫基... | CAS号148017-44-1 (2S,4S)-2-[[(氨基... | CAS号148017-42-9 (2S,4S)-4-(乙酰基硫... | CAS号40216-83-9 L-羟脯氨酸甲酯盐酸盐 | CAS号51-35-4 L-羟脯氨酸 | CAS号51154-06-4 (S)-1-(叔丁氧羰基)-2... | CAS号202477-59-6 (2S,4R)-1-(叔丁氧羰... | CAS号83623-78-3 (2S,4S)-4-苄基-1-... | CAS号84348-37-8 N-B°C-4-氧代-L-脯氨酸

L-羟基脯氨酸 以80的收率获得boc-L-羟脯氨酸
参考文献:Dicycloazaalkane Derivates,Preparation Processes And Medical Uses Thereof
标题:Dicycloazaalkane Derivates,Preparation Processes And Medical Uses Thereof
摘要:本发明涉及新的二环氮杂烷衍生物,其通式表示为(i),以及包含它们的制备方法,药物组合物以及用于治疗特别是二肽基肽酶抑制剂(dpp-Iv)的用途,其中通式(i)的每个取代基如规范中所定义.

专利信息

专利号:US-6962906-B2
优先权日:2000-03-14
标题 :Oligonucleotide analogues, methods of synthesis and methods of use
发明人：EFIMOV VLADIMIR; FERNANDEZ JOSEPH; ARCHDEACON DOROTHY; ARCHDEACON JOHN; CHAKHMAKHCHEVA OKSANA; BURYAKOVA ALLA; CHOOB MIKHAIL; HONDORP KYLE
权利人:ACTIVE MOTIF
摘要:The present invention relates generally to oligonucleotide analogues that include novel protein nucleic acid molecules (PNAs), particularly monomers, dimers, oligomers thereof and methods of making and using these oligonucleotide analogues. The PNAs of the present invention are characterized as including a variety of classes of molecules, such as, for example, hydroxyproline peptide nucleic acids (HypNA), and serine peptide nucleic acids (SerNA). The invention includes monomers, homodimers, heterodimers, homopolymers and heteropolymers of these and other oligonucleotide analogues. The present invention includes methods of using these oligonucleotide analogues in the detection and separating of nucleic acid molecules, including uses that include the utilization of oligonucleotide analogues on a solid support. The present invention also includes methods for purifying or separating nucleic acids, such as mRNA molecules, by hybridization with the oligonucleotides of the present invention. The present invention also includes the use of oligonucleotides of the present invention in antisense and homologous recombination constructs and methods.

专利号:WO-2006038119-A1
优先权日:2004-10-08
标题:Stereoselective synthesis of n-protected alkoxy prolines
发明人：VRIEZE DEREK CLINTON
权利人:WARNER LAMBERT CO; VRIEZE DEREK CLINTON
摘要:A process for preparing optically-active N-protected alkoxy prolines, including (2R,4R)-4-methoxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester is disclosed. The N-protected alkoxy prolines are useful for preparing various serine protease factor Xa inhibitors, which are useful for treating diseases associated with abnormal thrombosis.

专利号:US-2003059789-A1
优先权日:2000-03-14
标 题 :Oligonucleotide analogues, methods of synthesis and methods of use

专利号:EP-1263773-A4
优先权日:2000-03-14
标题:OLIGONUCLEOTIDE ANALOGUES, METHODS OF SYNTHESIS AND METHODS OF IMPLEMENTATION

专利号:EP-1725526-B1
优先权日:2004-02-26
标 题 :Method for preparing pyrrolidine oximes
发明人：NADLER WILLIAM; PUPOWICZ DORIS
权利人:SERONO LAB
摘要:The present invention is related to a new synthesis for preparing pyrrolidine oximes of general formula (I). The compounds of formula (I) are useful in the treatment and/or prevention of preterm labor, premature birth and dysmenorrhea.

专利号:WO-0168673-A1
优先权日:2000-03-14
标 题:Oligonucleotide analogues, methods of synthesis and methods of use