CAS: 13439-84-4; 1,1,2,3,3-Pentamethylguanidine

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相似化合物

80-70-6 29166-72-1 6145-42-2

上下游产品

dimethyl amine tetramethyl-isothiourea methylamine N,N,N',N'-tetramethylchlorformamidinium chloride -1.1.2.3.3-pentamethyl-isobiguanid2.4-Bis--1.1.2.3.3-pentamethyl-isobiguanid N-Benzoyl-N',N',N'',N''-tetramethyl-guanidin 4-allyl-4-benzyl-2-phenyloxazol-5(4H)-one

合成工艺路线路线简述

  • 合成目标产物 1,1,2,3,3-Pentamethyl Guanidine 主要起始原料 Tetramethyluronium Chloride) And Methylamine
  • (文献来源)合成步骤主要原料 Tetramethyluronium Chloride) 和 Methylamine
📜四甲基胍,硫酸二甲酯 以 N,N-二甲基甲酰胺 用作溶剂,化学反应 24.0H,反应生成1,1,2,3,3-五甲基胍
参考文献:Anion Exchange Polymer Electrolytes
标题:Anion Exchange Polymer Electrolytes
摘要:固体阴离子交换聚合物电解质和组成物,包括化学化合物,其中包括具有聚合物核心,间隔物a和鸟氨酸基团的化学化合物,所述化学化合物均匀分散在适当的溶剂中,并具有以下结构: 其中: I)a是具有结构o,S,So2,-nh-,-n(Ch2)N,其中n=1-10,-(Ch2)N-ch3-,其中n=1-10,So2-Ph,Co-Ph,其中r5,R6,R7和r8各自独立地为-h,-nh2,F,Cl,Br,Cn或c1-C6烷基,或其中任意组合; Ii)r9,R10,R11,R12或r13各自独立地为-h,-ch3,-nh2,-no,-chnch3,其中n=1-6,Hc═o-,Nh2C═o-,-chncooh,其中n=1-6,-(Ch2)N-c(Nh2)-cooh,其中n=1-6,-ch-(Cooh)-ch2-cooh,-ch2-ch(O-ch2Ch3)2,-(C═s)-nh2,-(C═nh)-n-(Ch2)Nch3,其中n=0-6,-nh-(C═s)-sh,-ch2-(C═o)-o-c(Ch3)3,-o-(Ch2)N-ch-(Nh2)-cooh,其中n=1-6,-(Ch2)N-ch═ch,其中n=1-6,-(Ch2)N-ch-cn,其中n=1-6,芳香族基,如苯基,苄基,苯氧基,甲基苄基,氮取代的苄基或苯基基团,卤素或卤素取代的甲基基团; Iii)其中该组成物适用于膜电极组件的使用.

海关参考信息

专利信息


专利号:US-10793495-B2
优先权日:2015-08-14
标 题:Synthesis of polyaryl substituted aryl compounds
发明人:BOULOS RAMIZ; FEUTRILL JOHN
权利人:BOULOS & COOPER PHARMACEUTICALS PTY LTD
摘要:A method for the synthesis of a aryl compound of Formula (1).n nU T-W—R 1 ) n    (1)

专利号:US-7888337-B2
优先权日:2007-08-31
标 题 :Synthesis of oseltamivir containing phosphonate congeners with anti-influenza activity
发明人:WONG CHI-HUEY; FANG JIM-MIN; SHIE JIUN-JIE; CHENG YIH-SHYUN EDMOND; JAN JIA-TSRONG
权利人:ACADEMIA SINICA
摘要:Novel phosphonate compounds are described. The compounds have activity as neuraminidase inhibitors against wild-type and H274Y mutant of H1N1 and H5N1 viruses. The present disclosure also provides an enantioselective synthetic route to known neuraminidase inhibitors oseltamivir and the anti-flu drug Tamiflu®, as well as novel phosphonate compounds, via D-xylose. Another efficient and flexible synthesis of Tamiflu and the highly potent neuraminidase inhibitor Tamiphosphor was also achieved in 11 steps and >20% overall yields from the readily available fermentation product (1S-cis)-3-bromo-3,5 -cyclohexadiene-1,2-diol. Most of the reaction intermediates were obtained as crystals without tedious purification procedures. The key transformations include an initial regio- and stereoselective bromoamidation of a bromoarene cis-dihydrodiol, as well as the final palladium-catalyzed carbonylation and phosphonylation.

专利号:US-7615638-B2
优先权日:2006-04-28
标题 :Synthesis of grossularines-1 and analogs thereof and method of use
发明人:HORNE DAVID A; JOVE RICHARD; NAM SANGKIL; YAKUSHIJIN KENICHI; YAKUSHIJIN FUMIKO Y
权利人:HOPE CITY
摘要:In one embodiment of the present invention, a synthesis of grossularine-1 and N,N-didesmethylgrossularine-1 2 and analogs thereof based on a novel oxidative dimerization-electrocyclization sequence of 2-amino-4-(3-indolyl)imidazoles derived from oxotryptamine 3 is described.

专利号:US-9738647-B2
优先权日:2009-12-24
标题:Methods for the synthesis of polycyclic guanidine compounds
发明人:GRIDNEV ALEXEI
权利人:NOVOMER INC; SAUDI ARAMCO TECH CO
摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.

专利号:US-5639877-A
优先权日:1993-07-30
标题:Intermediates in the synthesis of cephalosporins
发明人:LUDESCHER JOHANNES; MACHER INGOLF
权利人:BIOCHEMIE GMBH
摘要:Novel amidine salts of 7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid (=HACA), particular guanidine and diaza-bicyclo-alkylene salts, are useful as intermediates in the synthesis of cephalosporins.

专利号:US-9303056-B2
优先权日:2012-07-25
标题 :Monomer for synthesis of RNA, method for producing same, and method for producing RNA
发明人:KATAOKA MASANORI
权利人:UNIV KOCHI
摘要:The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I′): n nwherein R 1 is a protective group of the hydroxy group and R 2 is an alkyl group or the like.

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合成参考文献


摘要:S. J. Angyal and W. K. Warburton. J. Chem. Soc. 1951, 2492.
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