CAS: 13252-83-0; 4-Hydroxy-6-Methylcoumarin

相似化合物

18692-77-8 1076-38-6 55005-28-2

上下游产品

6-methyl-chromen-4-one 5-methyl-2-hydroxyacetophenone carbon monoxide aluminium trichloride SKI-190986 5-methyl-2-hydroxyacetophenone benzopyranobenzopyran-11-one7,10-dihydroxy-9-methoxy-6-(4-methoxyphenyl)-3-methyl-6H,11H-2benzopyrano4,3-c1benzopyran-11-one 5-(2-Hydroxy-5-methyl-phenyl)-2-methyl-2,4-dihydro-pyrazol-3-one

乙酸对甲酚酯置于aluminum (III) Chloride,Sodium Hydride体系中,化学反应生成4-羟基-6-甲基香豆素
参考文献:Synthesis,Anticancer Activity And Photophysical Properties Of Novel Substituted 2-Oxo-2H-Chromenylpyrazolecarboxylates
标题:Synthesis,Anticancer Activity And Photophysical Properties Of Novel Substituted 2-Oxo-2H-Chromenylpyrazolecarboxylates
摘要:2-Oxo-2H-Chromenylpyrazolecarboxylates (8A-H And 12A-Zb) Have Been Synthesized By [3 + 2] Cycloaddition Of 2H-Chromenophenylhydrazones (7A-H And 11A-W) With Diethyl/dimethylbut-2-Ynedioates. Phenylchromeno[4,3-C]Pyrazol-4(1H)-Ones (13I-N) Were Prepared From Corresponding Phenylhydrazones (7A-H) With Catalytic Amount Of Piperidine In Presence Of Pyridine As A Solvent At 100 Degrees C. All The Synthesized Compounds (8A-H,12A-Zb And 13A-N) Were Screened For Anticancer Activity Against Three Human Cancer Cell Lines Such As Prostate (Du-145),Lung Adenocarcinoma (A549),And Cervical (Hela) By Standard Mtt Assay Method. Further,Photophysical Properties (Uv And Fluorescence) For These Compounds Were Discussed. (C) 2013 Elsevier Masson Sas. All Rights Reserved.
Doi:10.1016/j.Ejmech.2013.03.042

专利信息

专利号:US-5510375-A
优先权日:1993-11-19
标 题 :Coumarin derivatives as protease inhibitors and antiviral agents
发明人：DOMAGALA JOHN M; HAGEN SUSAN E; LUNNEY ELIZABETH; TAIT BRADLEY D
权利人:WARNER LAMBERT CO
摘要:The present invention relates to novel coumarin derivatives and related compounds which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The coumarin derivatives are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized coumarins and of related structures.

专利号:CN-112517060-A
优先权日:2020-12-02
标题:Catalyst, application and synthesis method of 4-hydroxycoumarin derivatives

专利号:CN-106749296-A
优先权日:2017-03-16
标 题:Asymmetric synthesis method of chiral furo[3,2-c]chromene compounds

专利号:CN-106749296-B
优先权日:2017-03-16
标题:Asymmetric synthesis method of chiral furo[3,2-c]chromene compounds

专利号:CN-112517060-B
优先权日:2020-12-02
标 题 :Catalyst, application and synthesis method of 4-hydroxycoumarin derivatives