CAS: 13080-90-5; Bicyclo[2.2.1]Hept-5-En-2-Ol

相似化合物

6143-29-9 694-98-4 95-12-5

上下游产品

vinyl acetate endo-5-norbornen-2-ol bicycloheptene-5 one-2(-)-1S,4Sbicyclo2.2.1heptene-5 one-2 5-norbornenyl-2-acetate urea Toluene-4-sulfonic acid 2-((1S,4R)-4-propyl-cyclopent-2-enyl)-ethyl ester heptan-2-exo-ol5-endo-Bromo-6-exo-(phenylselenyl)bicyclo2.2.1heptan-2-exo-ol

5-降冰烯-2-基乙酸酯 反应生成5-降冰片烯-2-醇
参考文献:降冰片烯酮旋光色散的大溶剂化效应
标题:降冰片烯酮旋光色散的大溶剂化效应
摘要:(1 R,4 R)降冰片酮已在互补的气相和溶液相条件下进行了探查,以评估环境扰动的假定作用.基于线性反应理论的密度函数或耦合簇水平的综合量子化学计算无法定量地分离出分离的(气相)分子的比旋测量值,这表明可能需要更高阶的处理准确预测这种内在行为.已经发现色散光学活性对周围介质的性质(相位)具有实质性但出乎意料的依赖性,古老的lorentz局部场校正可以很好地再现溶剂介导的旋转色散趋势,
Doi:10.1002/anie.201306339

专利信息

专利号:US-6384228-B2
优先权日:1998-05-26
标题 :Method for synthesis of halopyridyl-azacyclopentane derivative and intermediate thereof
发明人：NODE MANABU; NAKAMURA DAISAKU; FUJIWARA TOSHIO; ICHIHASHI SHOGO
权利人:NIHON MEDIPHYSICS CO LTD
摘要:The present invention relates to a method for synthesis of an optically active halopyridyl-azacyclo-pentane derivative and the intermediate thereof which comprises preparing an optically active allene-1,3-dicarboxylic acid ester derivative from an optically active acetonedicarboxylic acid ester derivative and then proceeding through a 7-azabicyclo[2.2.1]heptane derivative to obtain the objective product.

专利号:US-2016318862-A1
优先权日:2013-09-25
标 题:Synthesis of delta 12-pgj3 and related compounds
发明人：NICOLAOU KYRIACOS C; HERETSCH PHILIPP; HALE CHRISTOPHER R H; EL GHZAOUI ABDELLATIF EL MARROUNI; PULUKURI KIRAN KUMAR; YU RUOCHENG; GROVE CHARLES
权利人:UNIV RICE WILLIAM M
摘要:In one aspect, the present invention provides novel derivatives of Δ 12 -PGJ 3 and modular synthetic pathways to obtaining Δ 12 -PGJ 3 and derivatives thereof. In some aspects, the present derivatives of Δ 12 -PGJ 3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.

专利号:US-5726344-A
优先权日:1994-07-13
标题 :Enantiomeric enrichment of bicyclic alcohols
发明人：WEST J BLAIR; DEVRIES Keith
权利人:BEND RES INC
摘要:There is disclosed a two-stage enzymatically catalyzed reaction for the selective preparation of the (R)-endo-isomer of norbornenol from a mixture containing all four stereo- and regioisomers of norbornenol, as well as the synthesis of the intermediate product comprising the enantiomerically enriched mono-ester of (R)-endo-norbornenol and a diacid, and of the enantiomerically enriched saturated alcohol (R)-endo-norborneol. There is also disclosed a method for the production of (R)-endo-norborne-2-ol, by chemical reduction of either the enantiomerically enriched monoester and subsequent hydrolysis, or by hydrolysis of the enantiomerically enriched monoester and then chemical reduction.

专利号:US-2002010339-A1
优先权日:1998-05-26
标 题:Method for synthesis of halopyridyl-acyclopentane derivative and intermediate thereof

专利号:US-4033982-A
优先权日:1974-10-16
标 题 :3,4,5-Trithiapolycyclo compounds and derivatives
发明人：HAY ALLAN S
权利人:GEN ELECTRIC
摘要:A process for the preparation of 3,4,5-trithiapolycyclo compounds is described which comprises the reaction of sulfur with bicyclo[2.2.1]hept-2-ene compounds carried out in the presence of (1) a phenol, and (2) a base. The process can be carried out either in the absence or presence of an inert organic solvent. The trithiapolycyclic compounds produced by this process are useful as monomers in the synthesis of polymers which can be employed as additives for lubricants, to produce effective coatings on solid substrates, or to produce fibers and films.

专利号:US-12378584-B2
优先权日:2018-06-13
标 题 :Methionine analogue synthesis
发明人：WILTSCHI BIRGIT; FLADISCHER PATRIK; OFFNER-MARKO LISA-RAMONA; HECKENBICHLER KATHRIN; BREINBAUER ROLF
权利人:ENGENES BIOTECH GMBH
摘要:The present invention relates to a method for preparing a methionine analogue, comprising contacting a host cell with L-homoserine and one or more nucleophiles and cultivating said host cell and said one or more nucleophiles of (a) in a fermentation broth to produce said methionine analogue, wherein said host cell encodes and stably expresses a L-homoserine-O-acetyl-transferase (HSAT) and an O-acetyl-L-homoserine sulfhydrylase (OAHS). The present invention also relates to host cells encoding and expressing such HSAT and OAHS, as well as uses thereof for producing a methionine analogue.