
专利信息
专利号:US-2019216736-A1
优先权日:2018-01-01
标题:Scale up synthesis of silicasome nanocarriers
专利号:US-2009298139-A1
优先权日:2006-02-28
标 题 :Method for Polymer Synthesis Using Microfluidic Enzymatic Cascade
发明人:ZOU JIN; KAPLAN DAVID L; ZOU JIN; WONG PETER Y; KAPLAN DAVID L
权利人:ZOU JIN; KAPLAN DAVID L; ZOU JIN; WONG PETER Y; KAPLAN DAVID L
摘要:The present invention discloses a method for producing polymers in a microscale device. The system utilizes a symmetrically branched system of microchannels interconnecting a plurality of loading decks and re-action chambers. The fluid flow is manipulated by the placement of capillary check valves, mixing areas, and microcomb filters. The system provides for cascading enzymatic biosynthesis pathways wherein any variety of enzymes and reactants can be introduced into the system to produce a final product.
专利号:US-10689413-B2
优先权日:2015-09-16
标 题 :Composition enriched in single isomer of NUC-1031 and preparation method and use thereof
发明人:YUAN JIANDONG; HUANG YANGQING; MIAO LINFENG; GU JIANING; LIANG CHAOHUA; WANG ZHENGYE; SUN ZHANLI
权利人:BRIGHTGENE BIO MEDICAL TECH CO LTD
摘要:Provided is a preparation method of a composition enriched in compound Sp-1. The method performs isomer separation on a reaction product from the first step, and then performs a two-step chemical synthesis, so as to prepare a composition comprising high-purity compound Sp-1, wherein the HPLC purity of the single isomer Sp-1 is 90% or more. Provided is a composition enriched in compound Sp-1. The composition has an inhibitory effect on tumor cell proliferation in vitro significantly higher than that of NUC-1031 and compound Rp-1. Also provided are the use of the composition, and a pharmaceutical composition comprising the composition and at least one pharmaceutically acceptable excipient.
专利号:IL-301746-A
优先权日:2017-10-18
标 题:Amine-substituted heterocyclic compounds as ehmt2 inhibitors, salts thereof, and methods of synthesis thereof
专利号:JP-2023036991-A
优先权日:2017-10-18
标 题:Amine-substituted heterocyclic compounds as ehmt2 inhibitors, salts thereof, and methods of synthesis thereof
专利号:EP-3697762-A1
优先权日:2017-10-18
标 题 :Amine-substituted heterocyclic compounds as ehmt2 inhibitors, salts thereof, and methods of synthesis thereof