CAS: 115414-49-8; N-((2R,3R,4R,5S,6R)-2-(Hexadecyloxy)-4,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3-yl)Acetamide

该化合物是一种化合物,其特征是长期缺氧六丁基环氧链和嗜血性甘蓝胺,这种两栖性质使其能有效地发挥表面活性剂的作用,便利水溶液中小鼠的形成;乙酰胺组的存在增强了其溶性和稳定性,使之适合生物化学和药物的各种应用;它经常用于药物运载系统的配制,从而可以改善缺水药物的溶性及生物利用率;此外,其结构特征可能有助于其作为聚膜活性剂的潜力,影响细胞的相互作用;该化合物通常通过玻璃相系反应合成,其特性可能受到诸如pH和温度等因素的影响;

英文名称N-((2R,3R,4R,5S,6R)-2-(Hexadecyloxy)-4,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3-yl)Acetamide
中文名称N-((2R,3R,4R,5S,6R)-2-(十六烷氧基)-4,5-二羟基-6-(羟甲基)四氢-2H-吡喃-3-基)乙酰胺
IUPAC名称N-((2R,3R,4R,5S,6R)-2-(hexadecyloxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide
其它别名十六烷基-2-乙酰氨基-2-脱氧-β-D-吡喃葡糖苷; Hexadecyl 2-Acetamido-2-Deoxy-Ss-D-Glucopyranoside
CAS编号115414-49-8
MFCD编号:MFCD08703744
分子式:C24H47NO6分子量:445.64
产品CID: 190674
产品分类有机原料→分子砌块→手性化合物→手性砌块

相似结构搜索
InChIKey: WKLPLHUPPYUENY-MRKXFKPJSA-N
InChI=1S/C24H47NO6/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30-24-21(25-19(2)27)23(29)22(28)20(18-26)31-24/h20-24,26,28-29H,3-18H2,1-2H3,(H,25,27)/t20-,21-,22-,23-,24-/m1
计算化学: 氢键受体数6.0氢键供体数4.0可旋转键数18.0

相似化合物

115414-47-6 147126-58-7 147025-06-7

MSDS等安全信息

上下游产品

hexadecyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside 1-Hexadecanol 2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)[1,2-d]-2-oxazolinehexadecyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside hexadecyl 2-acetamido-4,6-O-benzylidene-3-O-(D-1-carboxyethyl)-2-deoxy-β-D-glucopyranoside O-(hexadecyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine γ-benzyl ester

合成工艺路线路线简述

合成目标产物 Hexadecyl 2-Acetamido-2-Deoxy-Beta-D-Glucopyranoside 主要起始原料 Hexadecyl 2-Acetamido-3,4,6-Tri-O-Acetyl-2-Deoxy-Beta-D-Glucopyranoside
(文献来源)合成步骤主要原料 Hexadecyl 2-Acetamido-3,4,6-Tri-O-Acetyl-2-Deoxy-Beta-D-Glucopyranoside

📜十六烷基-2,3,4,6-四-氧-乙酰基-β-D-吡喃氨基葡萄糖苷置于sodium Methylate体系中,用甲醇,二氯甲烷用作溶剂,化学反应 1.0H,以98%的收率获得十六烷基-2-乙酰氨基-2-脱氧-β-D-吡喃葡糖苷
参考文献:Synthesis Of Glycosidic Analogues Of N-Acetylneuramoyl-L-Alanyl-D-Isoglutamine
标题:Synthesis Of Glycosidic Analogues Of N-Acetylneuramoyl-L-Alanyl-D-Isoglutamine
摘要:
Doi:10.1007/bf00598682