CAS: 115091-29-7; 4,4',4''-Tri-Tert-Butyl-2,2':6',2''-Terpyridine

相似化合物

33354-75-5 72036-41-0 33354-77-7

📜4-叔丁基吡啶置于[{(Mecn-2,6-Ipr2C6H3)2Ch}Mg(2,2,6,6-Tetramethylpiperidine)]体系中,用 四氢呋喃 用作溶剂,化学反应生成4,4'-二叔丁基-2,2'-二吡啶,4,4',4''-三叔丁基2,2',6'2''-曲吡啶
参考文献:β-二酮基氨基甲酸镁复合物介导的吡啶同质联轴器的结构和合成洞察力
标题:β-二酮基氨基甲酸镁复合物介导的吡啶同质联轴器的结构和合成洞察力
摘要:的反应[(迪普nacnac)的mg(tmp)](1)与4-Subtituted通过顺序的区域选择性金属化和1,2-加成吡啶前进到提供一系列对称4,4'--R 2-2,2'-联吡啶产率高,代表了联吡啶的新进入.有趣的是,1与2-Ome-吡啶的反应导致不对称联吡啶6的形成,这是由于杂环的c6-放大作用,然后是cc-C偶联步骤,再加上第二个非金属化的c2位置分子,然后消除[ Dipp Nacnacmgome] 2(7).合成与光谱和结构分析相结合有助于合理化导致观测到的反应性的基本过程,并阐明空间受限的β-二酮戊二酸酯配体在确定区域选择性中的关键作用.
Doi:10.1002/chem.201803297

专利信息

专利号:US-2023357286-A1
优先权日:2020-07-24
标 题:Ketone synthesis and applications
发明人：KISHI YOSHITO; UMEHARA ATSUSHI
权利人:HARVARD COLLEGE
摘要:Provided are new nickel./zirconium-mediated coupling reactions useful in the synthesis of ketone-containing compounds, e.g., halichondrin natural products and related molecules. A feature of the present disclosure is the use of a nickel(I) catalyst in tandem with a nickel (II) catalyst in the Ni/Zr-mediated coupling reactions. Without wishing to be bound by any particular theory, the nickel (I) catalyst selectively activates the electrophilic coupling partner (i.e., the compound of Formula (A)), and the nickel(ll) catalyst selectively activates the nucleophilic coupling partner (i.e., a thioester of Formula (B)). This dual catalyst system leads to improved coupling efficiency and eliminates the need for a large excess of one of the coupling partners (i.e., a compound of Formula (A) or (B)).

专利号:WO-2023061999-A1
优先权日:2021-10-12
标 题 :Process for preparing a phenolic hydrocarbon
发明人：CORNELLA JOSEP; LE VAILLANT FRANCK
权利人:STUDIENGESELLSCHAFT KOHLE GGMBH
摘要:The present invention discloses a distinct mode of action of a nickel catalyst to forge C-0 bonds to unlock the mild utilization of N2O as O-atom transfer reagent in the synthesis of complex phenols from the corresponding aryl halides.

专利号:US-9708336-B2
优先权日:2014-01-22
标题 :Metallo-beta-lactamase inhibitors
发明人：MANDAL MIHIR; TANG HAIFENG; XIAO LI; SU JING; LI GUOQING; YANG SHU-WEI; PAN WEIDONG; TANG HAIQUN; DEJESUS REYNALDA; HICKS JACQUELINE; LOMBARDO MATTHEW; CHU HONG; HAGMANN WILLIAM; PASTERNAK ALEX; GU XIN; JIANG JINLONG; DONG SHUZHI; DING FA-XIANG; LONDON CLARE; BISWAS DIPSHIKHA; YOUNG KATHERINE; HUNTER DAVID N; ZHAO ZHIQIANG; YANG DEXI
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

专利号:KR-102742314-B1
优先权日:2022-11-14
标题:A Synthesis and manufacturing method of organic boron compounds using nickel catalyst reaction

专利号:CN-111423299-B
优先权日:2019-01-10
标题:A photochemical catalytic synthesis method of aryl olefin compounds

专利号:CN-111423299-A
优先权日:2019-01-10
标 题:A kind of photochemical catalytic synthesis method of aryl olefin compounds