CAS: 625-08-1; 3-Hydroxy-3-Methylbutanoic Acid

相似化合物

2568-33-4 18267-36-2 37526-90-2

上下游产品

CAS号123-42-2 二丙酮醇 | CAS号1823-52-5 2,2-Dimethyloxe... | CAS号75-65-0 叔丁醇 | CAS号624-97-5 2-甲-4-戊烯-2-醇 | CAS号816-66-0 4-甲基-2-氧戊酸 | CAS号541-47-9 3,3-二甲基丙烯酸 | CAS号7601-90-3 高氯酸 | CAS号503-74-2 异戊酸 | CAS号871888-50-5 (±)-4-methyl-1,... | CAS号5292-12-6 tert-butyl 3-hy... | CAS号541-47-9 3,3-二甲基丙烯酸 | CAS号75-65-0 叔丁醇 | CAS号18267-36-2 乙基3-羟基-3-甲基丁酸酯 | CAS号6149-45-7 3-羟基-3-甲基丁酸甲酯

在 Lithium Hydroxide,水体系中,用 乙醇 作为反应溶剂,化学反应 3.0H,以91%的收率获得产物β-羟基异戊酸
参考文献:Synthesis Of Perhydrooxazinones From 2-Aza-3-Trimethylsilyloxy-1,3-Butadiene. A General Route To 3,3-Disubstituted-β-Hydroxy Acids
标题:Synthesis Of Perhydrooxazinones From 2-Aza-3-Trimethylsilyloxy-1,3-Butadiene. A General Route To 3,3-Disubstituted-β-Hydroxy Acids
摘要:1-苯基-2-氮-3-三甲基硅氧基-1,3-丁二烯与脂肪酮,芳香酮和环酮反应,能够以非常好至优异的收率获得产物6,6-二取代-1,3-过氢氧嗪-4-酮,而这些产物又可以容易地转化为β-羟基羧酸.
DOI:10.1055/s-1999-2926

专利信息

专利号:US-8420607-B2
优先权日:2006-06-30
标 题 :Anthrax carbohydrates, synthesis and uses thereof
发明人：CARLSON RUSSELL W; BOONS GEERT-JAN; QUINN CONRAD; VASAN MAHALAKSHMI; WOLFERT MARGREET A; BUSKAS THERESE; CHOUDHURY BISWA; KANNENBERG ELMAR; LEOFF CHRISTINE; MEHTA ALOK; SAILE ELKE; RAUVOLFOVA JANA; WILKINS PATRICIA
权利人:CARLSON RUSSELL W; BOONS GEERT-JAN; QUINN CONRAD; VASAN MAHALAKSHMI; WOLFERT MARGREET A; CHOUDHURY BISWA; KANNENBERG ELMAR; LEOFF CHRISTINE; MEHTA ALOK; SAILE ELKE; RAUVOLFOVA JANA; WILKINS PATRICIA; HARVEY ALEX J; UNIV GEORGIA; US HEALTH
摘要:The present invention presents the isolation, characterization and synthesis of oligosaccharides of Bacillus anthracis . Also presented are antibodies that bind to such saccharide moieties and various methods of use for such saccharide moieties and antibodies.

专利号:US-11807600-B2
优先权日:2021-11-12
标题 :Synthesis of novel ketone body analogs for use as a nutritional supplement
发明人：ROZZONI SAMUEL J; SAUER DARYL R
权利人:ROZZONI SAMUEL J; SAUER DARYL R
摘要:When a healthy and balanced diet is not achieved, nutritional supplements are used to help deal with the resulting health issues and enhance the body's performance. The present invention relates to a novel category of molecules that combine the properties of both ketone bodies and β-Hydroxy β-Methylbutyrate (HMB) that can be used as supplements for treating a wide range of health-related issues. Acetoacetate and β-Hydroxybutrate along with isopentyldiol were used as the sources of ketone bodies and HMB, respectively. The present invention provides a method of synthesis for a new group of compounds that incorporate the properties found in acetoacetate and 3-hydroxybutyrate molecules with that of β-hydroxy β-methylbutyrate.

专利号:US-9310366-B2
优先权日:2006-06-30
标题:Anthrax carbohydrates, synthesis and uses thereof
发明人：CARLSON RUSSELL W; BOONS GEERT-JAN; BUSKAS THERESE; KANNENBERG ELMAR; MEHTA ALOK; SAILE ELKE; QUINN CONRAD; WILKINS PATRICIA; VASAN MAHALAKSHMI; WOLFERT MARGREET A
权利人:UNIV GEORGIA; US HEALTH
摘要:The present invention presents the isolation, characterization and synthesis of oligosaccharides of Bacillus anthracis . Also presented are antibodies that bind to such saccharide moieties and various methods of use for such saccharide moieties and antibodies.

专利号:US-12234495-B2
优先权日:2021-04-06
标 题:Synthesis of beta-hydroxyisovalerate and methods of use
发明人：VEMURI GOUTHAM; LINDSAY CHRISTOPHER; ROBERG-PEREZ KEVIN; SNOW CHRISTOPHER D; CAMERON ELIZABETH A
权利人:SASYA INC
摘要:The biological production of beta-hydroxyisovalerate (βHIV) using at least one non-natural enzyme. The non-natural enzyme for the biologically-derived βHIV provides more beta-hydroxyisovalerate synthase activity than the wild-type parent. The non-natural enzyme having one or more modifications of substrate-specificity positions. The non-natural enzyme can be expressed in a microorganism, such as a yeast or bacteria, wherein the microorganism comprises an active βHIV metabolic pathway for the production of βHIV. Alternatively, the non-natural enzyme can be a βHIV synthase used to produce βHIV in a cell-free environment. The biological derivation of βHIV eliminates toxic by-products and impurities that result from the chemical production of βHIV, such that βHIV produced by a non-natural enzyme prior to any isolation or purification process has not been in substantial contact with any halogen-containing component.

专利号:US-7901687-B2
优先权日:2006-04-28
标 题 :Antibodies for the detection of Bacillus anthracis and vaccine against B. anthracis infections
发明人：WERZ DANIEL B; SEEBERGER PETER H; TAMBORRINI MARCO; PLUSCHKE GERD
权利人:ETH ZUERICH; SCHWEIZERISCHES TROPENINSTITUT
摘要:The present invention relates to conjugates of oligosaccharides of formula 1, wherein R is a linker to a carrier protein and optionally comprises up to three further saccharides, 5 and which are useful for vaccination, methods of synthesis of such conjugates, antibodies against this antigen, hybridoma producing monoclonal antibodies against this antigen, assays using these antibodies for the detection of B. anthracis spores and kits comprising these antibodies, and a vaccine for the prevention of B. anthracis infection comprising the conjugates of oligosaccharides of formula 1. Monoclonal antibodies 10 according to the invention selectively bind to B. anthracis , but not to related bacteria such as B. subtilis, B. cereus and other bacteria of this group such as B. thuringiensis .

专利号:WO-2020060469-A1
优先权日:2018-09-19
标 题:Process for utilization of gaseous by-products from fermentation processes
发明人：STIGSSON LARS
权利人:KIRAM AB
摘要:The present invention refers to a process for the production of biofuels or fine chemicals from biomass, said process comprising the following steps a) providing a carbonaceous material originating from biomass in a form suitable for fermentation b) fermentation of carbonaceous material from step a for production of at least one main fermentation product and a carbon dioxide containing gas c) recovering carbon dioxide containing gas from step b and after optional purification, combining carbon dioxide containing gas with a hydrogen containing gas to form a synthesis gas containing carbon monoxide and hydrogen d) converting synthesis gas comprising carbon monoxide and hydrogen by a catalytic process to provide biofuels or biofuel components; and e) transferring heat by heat transfer at least between process steps d) and process b) and c).