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CAS号54509-73-8 ethene | CAS号107-06-2 1,2-二氯乙烷 | CAS号74-84-0 乙烷 | CAS号624-73-7 1,2-二碘乙烷 | CAS号16670-48-7 苯磺酸2-氯乙酯 | CAS号7553-56-2 碘 | CAS号7732-18-5 水 | CAS号7790-99-0 一氯化碘 | CAS号75-05-8 乙腈 | CAS号54373-15-8 4-(2-氯乙氧基)苯甲醛 | CAS号22258-71-5 2(3H)-Benzothia... | CAS号107-21-1 乙二醇 | CAS号54509-73-8 ethene | CAS号107-06-2 1,2-二氯乙烷 | CAS号10034-85-2 氢碘酸 | CAS号7647-01-0 盐酸 | CAS号52548-84-2 1-(2-氯乙基)-2,3-二... | CAS号75-21-8 环氧乙烷 | CAS号107-04-0 1-溴-2-氯乙烷1,2-二碘乙烷置于一氯化碘体系中,化学反应生成 1-氯-2-碘乙烷
参考文献:Simpson,Justus Liebigs Annalen Der Chemie,1863,Vol. 125,P. 102
标题:Simpson,Justus Liebigs Annalen Der Chemie,1863,Vol. 125,P. 102
专利信息
专利号:US-4026911-A
优先权日:1976-02-23
标 题:Process for the preparation of ketoalkynoic acids and use of the process in an improved synthesis of 2-(substituted)-cyclo-pentane-1,3,4-triones
发明人:REVERMAN LAWRENCE FRANCIS
权利人:MILES LAB
摘要:Reaction of a 2-methyl-2-(alkenyl)-1,3-dioxolane with an α,ω-dihalogenoalkane to obtain a 2-methyl-2-(ω-chloroalkynyl)-dioxolane, conversion of the latter to a corresponding nitrile, and hydrolysis of the nitrile to form a ketoalkynoic acid is a novel process for preparing the acid. n Use of the process in the synthesis of 2-(substituted)-cyclopentane-1,3,4-triones improves that synthesis.
专利号:US-6310209-B1
优先权日:1997-12-08
标题:Synthesis of CC-1065/duocarmycin analogs
发明人:BOGER DALE L
权利人:SCRIPPS RESEARCH INST
摘要:The present invention relates to a method for the synthesis of the dihydroindole C-ring found in CC-1065/duocarmycin analogs.
专利号:US-4721788-A
优先权日:1985-07-12
标题:4-cyanopiperidine derivatives
发明人:YAMAUCHI HIROSHI; NOMOTO SEIICHIRO; SUGIYAMA ISAO; KOMATU YUUKI; KANAI TAKEO; TAKAYANAGI KEIZO; TANAKA YASUHIDE; KOIWA ATSUSHI; ENDOH SHINICHI
权利人:EISAI CO LTD
摘要:A novel 4-cyanopiperidine derivative, which is represented by the following general formula (I): ##STR1## wherein X means a halogen atom, or an acid addition salt thereof, is prepared by reacting N-(2-hydroxyethyl)-4-carbamoylpiperidine or an acid addition salt thereof with a dehydrating and halogenating agent; or by reacting 4-cyanopiperidine or a salt thereof with a compound represented by the following general formula (IV): n n X--CH.sub.2 CH.sub.2 --Y (IV) n n wherein X has the same meaning as defined above and Y denotes the same halogen atom as X or another halogen atom. The derivative is useful as intermediate for synthesis of quinuclidine derivative which is in turn useful as intermediate for the production of medicines, chemicals, etc.
专利号:DE-2707128-A1
优先权日:1976-02-23
标 题:PROCESS FOR THE PREPARATION OF KETOALKYNIC ACIDS AND APPLICATION OF THE PROCESS TO AN IMPROVED SYNTHESIS OF 2- (SUBSTITUTE) -CYCLOPENTANE-1,3,4-TRIONEN
专利号:EP-1037865-A1
优先权日:1997-12-08
标题 :Synthesis of cc-1065/duocarmycin analogs
专利号:EP-1037865-A4
优先权日:1997-12-08
标题:SYNTHESIS OF CC-1065 / DUOCARMYCIN ANALOGS