CAS: 623-93-8; 5-Nonanol

该化合物是直链脂醇,其特点是九碳结构,而氢氧(OH)功能组位于第五碳上,这种化合物在室温上是一种无色液体,表现出温和,脂肪味,在水中略有溶解,但在有机溶剂中更易溶,反映其非生殖性. 5诺诺诺醇因其在香气工业中的应用而闻名,用作气味成分,以及各种化学中间体的合成,与较小的酒精相比,其沸点相对较高,后者由于范德华尔斯的强度增加,是较慢链酒精的典型.此外,5诺诺诺醇可以参与各种化学反应,包括氧化和化,使其在有机合成中成为多用途化合物.安全数据表明,尽管它可能会在与皮肤或眼睛接触时引起刺激,但一般认为在正确处理时毒性较低.

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合成工艺路线路线简述

    📜5-壬酮置于pt/al2O3,氢气体系中,100.0 °C,4.0 Mpa 条件下,反应生成 5-壬醇
    参考文献:乙酰丙酸衍生的戊酸转化为煤油型液体运输燃料
    标题:乙酰丙酸衍生的戊酸转化为煤油型液体运输燃料
    摘要:在木质纤维素生物质向燃料和化学物质的转化中,非常需要形成碳碳键和增加疏水性.酮基脱羧完全符合这些要求,因为它将羧酸转化为形成一个碳碳键的酮,并消除了三个氧原子,如二氧化碳和水.该反应以级联方法与氢化和脱水催化剂一起用于从己糖衍生的戊酸获得煤油范围内的烃.结果表明,氧化锆对于该方法是非常选择性和稳定的催化剂,当与负载在氧化铝上的铂结合使用时,氧含量几乎降至零.此外,已证明氧化铝优于活性炭,二氧化硅,氧化锆或氧化锆作为加氢/脱水/加氢顺序的载体,并且钯基催化剂的失活速度比铂催化剂快.因此,在优化的反应条件下,戊酸被转化为在有机液相中具有80%选择性的正壬烷(连同10%的c 10-C 15碳氢化合物),进料与催化剂之比[w / W]高达100:1.模拟蒸馏证明,无氧烃产物混合物(85%的收率)与煤油的沸点范围非常吻合.在气相中,检测到丁烷和主要是二氧化碳.
    DOI:10.1016/j.Molcata.2013.11.015

    海关参考信息

    专利信息


    专利号:WO-2012163936-A1
    优先权日:2011-05-31
    标 题 :Process for the synthesis of benzotriazoles useful as uv-filters
    发明人:PRESCHEL MICHAEL; ROEDER MICHAEL; SCHLIFKE-POSCHALKO ALEXANDER; ZHANG KESHENG
    权利人:DSM IP ASSETS BV; PRESCHEL MICHAEL; ROEDER MICHAEL; SCHLIFKE-POSCHALKO ALEXANDER; ZHANG KESHENG
    摘要:The invention relates to an improved process for the manufacture of novel benzotriazoles as well to novel benzotriazoles obtained by the novel process. This novel economical process provides products in high purity and yields.

    专利号:US-10017465-B2
    优先权日:2014-08-12
    标 题 :Method for producing astaxanthin from astacin
    发明人:Schäfer Bernd; SIEGEL WOLFGANG
    权利人:BASF SE
    摘要:The invention relates to a method for the non-stereoselective and also for the stereoselective synthesis of astaxanthin from astacin. For this purpose, a reducing agent is used selected from the group of hydrogen, a secondary alcohol, formic acid and also the salts of formic acid or from a mixture of at least two representatives of the compound classes stated above. The invention further relates to the use of astacin as starting compound for the synthesis of astaxanthin.

    专利号:US-4803290-A
    优先权日:1987-05-29
    标 题 :Nonanol/nonene antimicrobial compositions
    发明人:BURKE BASIL A; NAIR MURALEEDHARAN
    权利人:PCRI INC
    摘要:Substituted 5'-nonanol/5'-nonene compounds which exhibit important antimicrobial and antifungal activity, compositions and methods of delivery against pathovars and pathogens, and methods of synthesis from commonly available reactants. The antimicrobial composition active ingredient is one or more substituted 1,2-alkylidenedioxybenzene compounds of the formula: where R3 is selected from 5'-nonanol and 5'-nonene, and R1 and R2 are selected from H and C1-C5 alkyl, alkenyl and alkynyl groups. The preferred compounds are 5-(5'-hydroxy- 5'- nonanyl)-1,1-methylenedioxybenzene and 4-(5'-non-4'-enyl)-1,2-methylenedioxybenzene. Compositions including these compounds exhibit antimicrobial activity against a variety of pathogens and pathovars, e.g., Xanthomonas campestris spp. bacteria, antifungal activity against a variety of fungi and bacteria, and are highly specific, e.g., having antifungal activity against wheat powdery mildew and cucumber downy mildew, but do not affect seed germination or have appreciable herbicidal or insecticidal activity. Methods and compositions for delivery of these agents against such pathogens, and methods of chemical synthesis of the compounds are disclosed.

    专利号:CN-109689727-A
    优先权日:2016-07-27
    标题:Process for the regioselective synthesis of polyesters from asymmetric diols

    专利号:CN-213202875-U
    优先权日:2020-09-29
    标 题 :Separation system for aqueous phase byproducts of Fischer-Tropsch synthesis reaction

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    合成参考文献


    摘要:Zaidlewicz, M.; Krzemiński, M. P.; Dzieleńdziak, A., Science of Synthesis, (2009) 48, 388.
    摘要:Campagne, J. M.; Leclerc, E., Science of Synthesis Knowledge Updates, (2020) 2, 154.
    摘要:Singh, F. V.; Wirth, T., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 45.
    摘要:Li, H.; Wang, Y.; Liu, Q., Science of Synthesis: Base-Metal Catalysis, (2023) 2, 511.
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