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4-oxo-2,2,6,6-tetramethylpiperidin-oxyl [(p-methylphenyl)sulfonylmethyl]isonitrile 1-hydroxy-4-cyano-2,2,6,6-tetramethylpiperidinium chloride 2,2,6,6-Tetramethyl-4-piperidone 1-oxyl-4-carboxyl-2,2,6,6-tetramethylpiperidine 专利信息
专利号:WO-2013182636-A1
优先权日:2012-06-07
标 题 :Synthesis of a viral protease inhibitor
发明人:ALLEGRINI PIETRO; BRUNOLDI ENRICO; ATTOLINO EMANUELE
权利人:DIPHARMA FRANCIS SRL
摘要:Disclosed is a process for the preparation of telaprevir of formula (I) or a salt thereof, comprising the oxidation reaction of a compound of formula (II) or a salt thereof, (II) wherein said oxidation is conducted in a solvent in the presence of a supported oxidising agent.
专利号:WO-2024237180-A1
优先权日:2023-05-16
标题 :(meth)acrylate compound production method
发明人:NAKAKURA KOKI; SHIRAI SHINYOU
权利人:MITSUBISHI GAS CHEMICAL CO
摘要:The present invention provides, inter alia, a (meth)acrylate compound production method capable of suppressing polymerization of a feedstock acrylic acid ester at the time of synthesis and obtaining a reaction product having higher purity. The (meth)acrylate compound production method according to the present invention is characterized by comprising at least a step for carrying out an ester exchange reaction of spiroglycol and a (meth)acrylic acid ester in the presence of a polymerization inhibitor, the polymerization inhibitor containing an N-oxyl compound and a polymerization inhibitor having a boiling point of 246°C or less.