专利号:US-8420850-B2 优先权日:2010-05-14 标 题:Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers 发明人:DUOCASTELLA CODINA LLUIS; MOLINA MARIA; ARAD OFIR; BORRELL BILBAO JOSE IGNACIO; GARCIA DAVID SANCHEZ; PETTERSON SALOM SOFIA HENRIETTE 权利人:DUOCASTELLA CODINA LLUIS; MOLINA MARIA; ARAD OFIR; BORRELL BILBAO JOSE IGNACIO; GARCIA DAVID SANCHEZ; PETTERSON SALOM SOFIA HENRIETTE; IBERHOSPITEX SA 摘要:The invention comprises compounds which are derived from a drug or a substance with therapeutic properties, and useful as reagents for the synthesis of biostable polymers including said drug in their backbone, namely polyurethanes, polyureas or polyurea urethanes that are biocompatible and biostable. The invention also comprises the processes for preparing the compounds and the polymers, and to the use of these polymers for the manufacture of medical devices.
专利号:US-11667666-B2 优先权日:2020-01-20 标题 :Methods and compositions for treatment of cancer 发明人:SINGHAL ANUJ 权利人:CFD RES CORPORATION 摘要:In an aspect, the disclosure pertains to inhibitors of ANGPTL4; synthesis methods for making disclosed compounds; pharmaceutical compositions comprising disclosed compounds; methods of treating disorders of uncontrolled cellular proliferation, e.g., a cancer; and methods of treating a disease associated with an ANGPTL4 dysfunction using disclosed compounds and pharmaceutical compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
专利号:US-2012059117-A1 优先权日:2010-05-14 标 题 :Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers
专利号:WO-2011141341-A1 优先权日:2010-05-14 标题:Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers
专利号:EP-2569015-A1 优先权日:2010-05-14 标题 :Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers
专利号:US-2014315720-A1 优先权日:2012-10-24 标 题 :Polysaccharide ester microspheres and methods and articles relating thereto 发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY 权利人:CELANESE ACETATE LLC 摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
1: Egesel T, Unsal I, Dikmen G, Bayraktar Y. The assessment of pancreatic exocrine function by bentiromide test in patients with chronic portal vein thrombosis. Pancreas. 2002 Nov;25(4):355-9. Review. Japanese.
合成参考文献
摘要:Iyakuhin Kenkyu. Study of Medical Supplies., 11(181), 1980 摘要:Yang XO, Li JN, Qian JM. [The role of fecal elastase-1 in pancreatic diseases]. Zhonghua Nei Ke Za Zhi. 2006 Apr;45(4):285–8. 参考文献:10.1111/j.1751-2980.2011.00498.x 摘要:Ito T, Nakamura T, Fujimori N, Niina Y, Igarashi H, Oono T, Uchida M, Kawabe K, Takayanagi R, Nishimori I, Otsuki M, Shimosegawa T. Characteristics of pancreatic diabetes in patients with autoimmune pancreatitis. J Dig Dis. 2011 Jun;12(3):210–6. doi: 10.1111/j.1751-2980.2011.00498.x. 参考文献:10.1016/s0022-3476(05)81798-6 摘要:Durie PR, Yung-Jato LY, Soldin SJ, Verjee Z, Ellis L. Bentiromide test using liquid-chromatographic measurement of p-aminobenzoic acid and its metabolites for diagnosing pancreatic insufficiency in childhood. The Journal of Pediatrics. 1992 Sep;121(3):413–6. doi: 10.1016/s0022-3476(05)81798-6. 参考文献:10.1371/journal.pone.0002278 摘要:Oneda B, Lods N, Lottaz D, Becker-Pauly C, Stöcker W, Pippin J, Huguenin M, Ambort D, Marti HP, Sterchi EE. Metalloprotease meprin beta in rat kidney: glomerular localization and differential expression in glomerulonephritis. PLoS One. 2008 May 28;3(5):e2278.