CAS: 37106-97-1; (S)-4-(2-Benzamido-3-(4-Hydroxyphenyl)Propanamido)Benzoic Acid

该化合物是一种属于氨基酸和衍生物类的化学化合物,具有与氨基酸乙酸乙酰胺进一步相连的苯并基组,与氨基苯并氨基乙酰酸混合物有进一步的联系.该化合物显示出氨基酸的典型特征,包括有矿和碳酸功能组,允许其参与各种生物化学反应.由于其离子体和极地功能组,该化合物很可能溶于极地溶剂中.该化合物可能展示生物活动,有可能作为基质或抑制剂在酶反应中发挥作用,并可能对药物应用感兴趣.其结构成分表明,该化合物还可能具有紫外吸附性,这可能与皮肤保护配方有关.与氨基酸的许多衍生物一样,其稳定性和再活性可能受到pH和温度的影响,因此在实际应用中考虑这些因素十分重要.

结构式图片

上下游产品

N-苯甲酰-L-酪氨酸 N-Benzoyl-L-Tyrosine 2566-23-6
N-苯甲酰基-L-酪氨酸甲酯 N-Benzoyl-L-Tyrosine Methyl Ester 10418-01-6

合成工艺路线路线简述

    📜Methyl (S)-4-(2-Benzamido-3-(4-Hydroxyphenyl)Propanamido)Benzoate置于lithium Hydroxide Monohydrate体系中,用 四氢呋喃,水 作为反应溶剂,以95 %的收率获得产物胰功定
    参考文献:通过氨基酸插入实现酰胺骨架伸长
    标题:通过氨基酸插入实现酰胺骨架伸长
    摘要:报道了一种通过两个串联分子内重排实现的氨基酸插入的新酰胺键激活范例.该策略仅需要稳定且易于获得的酰胺和氨基酸作为起始原料,不需要任何预官能化以及反应中间体的分离.
    DOI:10.1002/chem.202301729

    海关参考信息

    专利信息


    专利号:US-8420850-B2
    优先权日:2010-05-14
    标 题:Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers
    发明人:DUOCASTELLA CODINA LLUIS; MOLINA MARIA; ARAD OFIR; BORRELL BILBAO JOSE IGNACIO; GARCIA DAVID SANCHEZ; PETTERSON SALOM SOFIA HENRIETTE
    权利人:DUOCASTELLA CODINA LLUIS; MOLINA MARIA; ARAD OFIR; BORRELL BILBAO JOSE IGNACIO; GARCIA DAVID SANCHEZ; PETTERSON SALOM SOFIA HENRIETTE; IBERHOSPITEX SA
    摘要:The invention comprises compounds which are derived from a drug or a substance with therapeutic properties, and useful as reagents for the synthesis of biostable polymers including said drug in their backbone, namely polyurethanes, polyureas or polyurea urethanes that are biocompatible and biostable. The invention also comprises the processes for preparing the compounds and the polymers, and to the use of these polymers for the manufacture of medical devices.

    专利号:US-11667666-B2
    优先权日:2020-01-20
    标题 :Methods and compositions for treatment of cancer
    发明人:SINGHAL ANUJ
    权利人:CFD RES CORPORATION
    摘要:In an aspect, the disclosure pertains to inhibitors of ANGPTL4; synthesis methods for making disclosed compounds; pharmaceutical compositions comprising disclosed compounds; methods of treating disorders of uncontrolled cellular proliferation, e.g., a cancer; and methods of treating a disease associated with an ANGPTL4 dysfunction using disclosed compounds and pharmaceutical compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

    专利号:US-2012059117-A1
    优先权日:2010-05-14
    标 题 :Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers

    专利号:WO-2011141341-A1
    优先权日:2010-05-14
    标题:Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers

    专利号:EP-2569015-A1
    优先权日:2010-05-14
    标题 :Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers

    专利号:US-2014315720-A1
    优先权日:2012-10-24
    标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
    发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
    权利人:CELANESE ACETATE LLC
    摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Egesel T, Unsal I, Dikmen G, Bayraktar Y. The assessment of pancreatic exocrine function by bentiromide test in patients with chronic portal vein thrombosis. Pancreas. 2002 Nov;25(4):355-9. Review. Japanese.

    合成参考文献


    摘要:Iyakuhin Kenkyu. Study of Medical Supplies., 11(181), 1980
    摘要:Yang XO, Li JN, Qian JM. [The role of fecal elastase-1 in pancreatic diseases]. Zhonghua Nei Ke Za Zhi. 2006 Apr;45(4):285–8.
    参考文献:10.1111/j.1751-2980.2011.00498.x
    摘要:Ito T, Nakamura T, Fujimori N, Niina Y, Igarashi H, Oono T, Uchida M, Kawabe K, Takayanagi R, Nishimori I, Otsuki M, Shimosegawa T. Characteristics of pancreatic diabetes in patients with autoimmune pancreatitis. J Dig Dis. 2011 Jun;12(3):210–6. doi: 10.1111/j.1751-2980.2011.00498.x.
    参考文献:10.1016/s0022-3476(05)81798-6
    摘要:Durie PR, Yung-Jato LY, Soldin SJ, Verjee Z, Ellis L. Bentiromide test using liquid-chromatographic measurement of p-aminobenzoic acid and its metabolites for diagnosing pancreatic insufficiency in childhood. The Journal of Pediatrics. 1992 Sep;121(3):413–6. doi: 10.1016/s0022-3476(05)81798-6.
    参考文献:10.1371/journal.pone.0002278
    摘要:Oneda B, Lods N, Lottaz D, Becker-Pauly C, Stöcker W, Pippin J, Huguenin M, Ambort D, Marti HP, Sterchi EE. Metalloprotease meprin beta in rat kidney: glomerular localization and differential expression in glomerulonephritis. PLoS One. 2008 May 28;3(5):e2278.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知