CAS: 33301-41-6; 1-Benzhydrylazetidin-3-Yl Methanesulfonate

上下游产品

CAS号18621-17-5 N-二苯甲基氮杂环丁烷-3-醇 | CAS号124-63-0 甲基磺酰氯 | CAS号90604-02-7 1-二苯甲基-3-羟基氮杂环丁烷盐酸盐 | CAS号91-00-9 二苯甲胺 | CAS号63477-43-0 1-(二苯甲基氨基)-3-氯丙烷-2-醇 | CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号53871-06-0 1-二苯甲基氮杂环丁烷-3-甲酸甲酯 | CAS号36476-86-5 1-二苯甲基-3-氰基氮杂环丁烷 | CAS号36476-88-7 1-(二苯基甲基)-3-氮杂环丁烷甲胺 | CAS号40432-52-8 3-氨基-1-二苯甲基氮杂环丁烷 | CAS号181941-94-6 2-(1-二苯甲基氮杂啶-3-... | CAS号72351-36-1 1-二苯甲基-3-羟甲基-氮杂环丁烷 | CAS号101-81-5 二苯甲烷 | CAS号107128-00-7 1-二苯甲基氮杂环丁烷 | CAS号125735-40-2 1-二苯甲基-3-碘氮杂环丁烷

二苯甲胺置于三乙胺体系中,用 二氯甲烷,异丙醇 用作溶剂,化学反应 30.5H,反应生成1-二苯甲基-3-甲烷磺酸氮杂环丁烷
参考文献:阿昔洛汀作为生物正交逆电子需求迪尔斯-阿尔德结扎中的亲二烯体.
标题:阿昔洛汀作为生物正交逆电子需求迪尔斯-阿尔德结扎中的亲二烯体.
摘要:开发了一种新的生物正交n-酰基腺苷标记,适用于四嗪介导的电子逆diels-Alder共轭逆反应.标签很小且非手性.我们展示了基于两步活动的基于蛋白质的蛋白质分析中基于n-酰基la丁嗪-四嗪的生物正交化学的有用性.在催化活性的蛋白酶体亚基标记中,新的四嗪亲和剂的性能与空间要求更高的降冰片烯标签的性能相当.
Doi:10.1021/ol501049C

专利信息

专利号:WO-2018108954-A1
优先权日:2016-12-12
标题 :Process for the preparation of 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol
发明人：GOSSELIN FRANCIS; LINGHU XIN
权利人:HOFFMANN LA ROCHE; GENENTECH INC
摘要:Methods of making 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol 9, an intermediate useful for the synthesis of estrogen receptor modulating compounds are described.

专利号:US-8071788-B2
优先权日:2004-10-14
标题:Method and intermediates for the preparation of derivatives of N-(1-benzhydrylazetidin-3-yl)-N-phenylmethylsulfonamide
发明人：BOFFELLI PHILIPPE; DELTHIL MICHEL; GRONDARD LUC; LAMPILAS MAXIME; MALPART JOEL; MUTTI STEPHANE; NAIT-BOUDA LAHLOU; REIKE-ZAPP JOERG
权利人:BOFFELLI PHILIPPE; DELTHIL MICHEL; GRONDARD LUC; LAMPILAS MAXIME; MALPART JOEL; MUTTI STEPHANE; NAIT-BOUDA LAHLOU; REIKE-ZAPP JOERG; SANOFI AVENTIS
摘要:The invention relates to a novel method for the synthesis of N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5 -difluorophenyl)methylsulfonamide.

专利号:US-4943641-A
优先权日:1984-02-27
标 题:3-aminoazetidine, its salts, process for their preparation and intermediates of synthesis
发明人：NISATO DINO; FRIGERIO MARCO
权利人:SANOFI SA
摘要:The 3-aminoazetidine, its salts, new intermediates of formula wherein X' represents hydrogen or a protecting group and both X'' represent hydrogen or, together with the nitrogen atom, a phthalimido group, X' not and both X'' being hydrogen at the same time; a process for the preparation of the 3-aminoazetidine, starting from a 1-protected 3-sulfonyloxyazetidine by reaction with the potassium phthalimide and transformation of the above mentioned intermediates.

专利号:US-4822895-A
优先权日:1984-02-27
标题:3-aminoazetidine, its salts and intermediates of synthesis

专利号:RU-2158264-C2
优先权日:1996-01-05
标 题 :3-azethidinylalkylpiperidines or pyrrolidines as tachykinine antagonists, methods of their synthesis, intermediate compounds, pharmaceutical composition based on thereof and method of treatment

专利号:RU-2097383-C1
优先权日:1992-03-11
标题:Carbopenem derivatives and a method of their synthesis