CAS: 77-46-3; Acedapsone

上下游产品

4-nitrophenyl sulfone 4,4'-bis(acetylamino)diphenyl sulfide N-[4-(4-Nitro-benzenesulfonyl)-phenyl]-acetamide 4,4'-di-N-acetylaminodiphenyl sulfoxide 6,6'-diamino-3,3'-sulfonyl-bis-benzenesulfonic acid diamide 3,3',4,4'-Tetraaminodiphenylsulfon dapsone 3,3'-dibromo-4,4'-diacetaminodiphenyl sulphone

📜4-乙酰氨基苯硫酚置于iron(Iii) Chloride,硫酸,双氧水,1-丁基-3-甲基咪唑二(三氟甲基磺酰)酰亚胺体系中,用 氯仿,水 作为反应溶剂,化学反应 121.0H,反应生成 N-[4-(4-乙酰氨基苯基)磺酰基苯基]乙酰胺
参考文献:三氟化铁(iii)催化富电子芳烃的区域选择性c-h硫杂芳基化
标题:三氟化铁(iii)催化富电子芳烃的区域选择性c-h硫杂芳基化
摘要:描述了一种使用铁(iii)催化制备不对称联芳基硫化物的温和区域选择性方法.的活化ñ-使用强大的路易斯酸铁(iii)三氟甲(芳硫基)琥珀酰亚胺允许的范围芳烃,包括苯甲醚,酚,乙酰苯胺的有效硫醇化,并ñ-Heterocycles.该方法适用于酪氨酸和色氨酸衍生物的后期硫醇化,并用作合成药学上相关的联芳基含硫化合物(如抗生素氨苯砜和抗抑郁药vortioxetine)的关键步骤.动力学研究表明,当n带有电子缺陷芳烃的-(芳硫基)琥珀酰亚胺完全由三氟甲磺酸铁(iii)催化硫代芳基化,带有富电子芳烃的n-(芳硫基)琥珀酰亚胺表现出路易斯基本产物促进的自催化机理.
DOI:10.1021/acs.Joc.1C00448

专利信息

专利号:US-12392085-B2
优先权日:2020-04-28
标题 :Use of in-situ ionic liquid (IL) and deep eutectic solvent (DES) synthesis using chemically synthesized or biomass-derived ions in the pretreatment of biomass
发明人：MAGURUDENIYA HARSHA D; ACHINIVU EZINNE; SIMMONS BLAKE A; GLADDEN JOHN M
权利人:UNIV CALIFORNIA; NATIONAL TECH AND ENGINEERING SOLUTIONS OF SANDIA LLC; NAT TECH & ENG SOLUTIONS SANDIA LLC
摘要:The present invention provides for a method to deconstruct a biomass comprising: (a) introducing one or more individual components of an ionic liquid (IL) or deep eutectic solvent (DES) to a biomass, wherein the one or more individual components, and optionally any components already present in the biomass, form an IL or DES, or mixture thereof, which solubilizes the biomass to form a solubilized biomass mixture, wherein at least one individual component is introduced to the biomass separately from any other individual component; (b) optionally introducing an enzyme and/or a microbe to the solubilized biomass mixture such that the enzyme and/or microbe produces a sugar from the solubilized biomass mixture; and, (c) optionally separating the sugar from the solubilized biomass mixture.

专利号:US-9693999-B2
优先权日:2011-01-26
标题:Small molecule RNase inhibitors and methods of use
发明人：DUNMAN PAUL M; OLSON PATRICK D; CHILDERS WAYNE
权利人:UNIV ROCHESTER; UNIV NEBRASKA; Temple University—Of the Commonwealth System of Higher Education
摘要:Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.

专利号:WO-2009056955-A1
优先权日:2007-10-30
标题 :Amine-bearing phospholipids (abps), their synthesis and use
发明人：ZUMBUEHL ANDREAS
权利人:UNIV BASEL; ZUMBUEHL ANDREAS
摘要:Disclosed herein are amine-bearing phospholipids (ABP). The ABPs display many properties and functionalities of naturally occurring phospholipids, but also new properties and functionalities, such as the ability to polymerize while maintaining structural integrity, that may supplement or expand the functionalities of naturally occurring phospholipids.

专利号:US-9868747-B2
优先权日:2014-02-18
标题:Marinopyrrole derivatives and methods of making and using same
发明人：LI RONGSHI; SEBTI SAID; LIU YAN; QIN YONG; SONG HAO; CHENG CHUNWEI
权利人:H LEE MOFFITT CANCER CT & RES; CHONGQING ZEIN PHARMACEUTICAL CO LTD
摘要:Marinopyrrole derivatives and methods for their synthesis and use are described herein. Novel cyclic and symmetric marinopyrroles with triazole substituents having antibacterial activity against resistant bacterial strains, such as MRSA are introduced. Also provided are methods of using the compounds for treating or preventing cancer and/or microbial infections.

专利号:US-9907753-B2
优先权日:2010-03-19
标 题 :Lipid vesicle compositions and methods of use
发明人：IRVINE DARRELL J; MOON JAEHYUN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.